Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1773241 | 1.00 | FAAH (0.41) | FAAHNPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL1775045 | 1.00 | FAAH (0.41) | FAAHNPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL1773435 | 0.85 | GPR119 (0.44) | FAAHSMN1; SMN2MAPTLMNA | |
| SCHEMBL1773437 | 0.85 | GPR119 (0.44) | FAAHSMN1; SMN2MAPTLMNA | |
| SCHEMBL1773618 | 0.85 | GPR119 (0.44) | FAAHSMN1; SMN2MAPTLMNA | |
| SCHEMBL3431702 | 0.84 | MTNR1A (0.34) | FAAHNPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL1966097 | 0.84 | MTNR1A (0.34) | FAAHNPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL1966094 | 0.84 | MTNR1A (0.34) | FAAHNPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL3376521 | 0.82 | FAAH (0.38) | FAAHNPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL27828628 | 0.82 | MTNR1A (0.36) | FAAHNPC1KDM4ERAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943774-B2 | Heterocyclyl-substituted thiazoles as crop protection agents | BAYER CROPSCIENCE AG (DE) | 2011-05-17 | — | — | US | disclosed |
| US-20100137245-A1 | Heteerocyclyl-substituted thiazoles as crop protection agents | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137245-A1 | Heteerocyclyl-substituted thiazoles as crop protection agents | CYP8B1, CYP51A1, HPD | FAAH 4083/4885NPC1 1772/4885KDM4E 3603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.