Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.73 |
| ▸ | LMNA | P02545 | 6/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | POLB | P06746 | 2/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.73 |
| ▸ | GALR2 | O43603 | 1/20 | 0.73 |
| ▸ | MITF | O75030 | 1/20 | 0.73 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.73 |
| ▸ | XBP1 | P17861 | 1/20 | 0.73 |
| ▸ | CCR6 | P51684 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.48 |
| ▸ | LTK | P29376 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL670956 | 0.87 | ALDH1A1 (0.57) | ALDH1A1LMNASMN1; SMN2POLBNPSR1 | |
| SCHEMBL9944758 | 0.86 | ALDH1A1 (0.56) | ALDH1A1LMNASMN1; SMN2POLBNPSR1 | |
| SCHEMBL1725104 | 0.84 | ALDH1A1 (0.71) | ALDH1A1LMNASMN1; SMN2POLBNPSR1 | |
| SCHEMBL670959 | 0.83 | ALDH1A1 (0.57) | ALDH1A1LMNASMN1; SMN2POLBNPSR1 | |
| SCHEMBL29405447 | 0.83 | NPSR1 (0.50) | ALDH1A1LMNASMN1; SMN2POLBNPSR1 | |
| SCHEMBL9898390 | 0.82 | ALDH1A1 (0.55) | ALDH1A1LMNASMN1; SMN2POLBNPSR1 | |
| SCHEMBL1969432 | 0.82 | ALDH1A1 (0.64) | ALDH1A1LMNASMN1; SMN2POLBNPSR1 | |
| SCHEMBL9793657 | 0.81 | SMN1; SMN2 (0.67) | ALDH1A1LMNASMN1; SMN2POLBNPSR1 | |
| SCHEMBL17930514 | 0.81 | ALDH1A1 (0.56) | ALDH1A1LMNASMN1; SMN2POLBNPSR1 | |
| SCHEMBL1965597 | 0.81 | NPSR1 (0.49) | ALDH1A1LMNASMN1; SMN2POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916599-B2 | 1H-benz imidazole-5-carboxamides as anti-inflammatory agents | OREXO AB (SE) | 2014-12-23 | — | — | US | disclosed |
| US-20110312935-A1 | 1H-Benz Imidazole-5-Carboxamides As Anti-Inflammatory Agents | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-12-22 | — | — | US | disclosed |
| EP-2334652-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | Boehringer Ingelheim International GmbH (DE) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010034796-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110312935-A1 | 1H-Benz Imidazole-5-Carboxamides As Anti-Inflammatory Agents | MAPRE2, MAPRE1, H1-4 | ALDH1A1 1202/4885LMNA 2823/4885SMN1; SMN2 3446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.