Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | GALR2 | O43603 | 1/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.56 |
| ▸ | CCR6 | P51684 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL670956 | 0.88 | ALDH1A1 (0.57) | ALDH1A1LMNAPOLBSMN1; SMN2GALR2 | |
| SCHEMBL9898390 | 0.88 | ALDH1A1 (0.55) | ALDH1A1LMNAPOLBSMN1; SMN2GALR2 | |
| SCHEMBL1966149 | 0.86 | ALDH1A1 (0.73) | ALDH1A1LMNAPOLBSMN1; SMN2GALR2 | |
| SCHEMBL1967194 | 0.85 | ALDH1A1 (0.49) | ALDH1A1LMNAPOLBSMN1; SMN2GALR2 | |
| SCHEMBL17008983 | 0.85 | ALDH1A1 (0.56) | ALDH1A1LMNAPOLBSMN1; SMN2GALR2 | |
| SCHEMBL17937026 | 0.84 | HCAR3 (0.49) | ALDH1A1LMNAPOLBSMN1; SMN2GALR2 | |
| SCHEMBL8191133 | 0.84 | LMNA (0.53) | ALDH1A1LMNAPOLBSMN1; SMN2GALR2 | |
| SCHEMBL670959 | 0.84 | ALDH1A1 (0.57) | ALDH1A1LMNAPOLBSMN1; SMN2GALR2 | |
| SCHEMBL17930514 | 0.82 | ALDH1A1 (0.56) | ALDH1A1LMNAPOLBSMN1; SMN2GALR2 | |
| SCHEMBL25352364 | 0.81 | ALDH1A1 (0.53) | ALDH1A1LMNAPOLBSMN1; SMN2GALR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674113-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-03-18 | — | — | US | disclosed |
| US-20120149676-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149676-A1 | NOVEL COMPOUNDS | PTGS1, PTGER1, PTGES | ALDH1A1 126/4885LMNA 1817/4885POLB 2315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.