Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27997543 | 0.82 | MEN1 (0.46) | TDP1KDM4EDUSP3MEN1KMT2A | |
| SCHEMBL8946732 | 0.80 | KDM4E (0.61) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL1685688 | 0.80 | LMNA (0.50) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL9504297 | 0.80 | TDP1 (0.68) | TDP1KDM4EKMT2ALMNAHSD17B10 | |
| SCHEMBL27916965 | 0.79 | MEN1 (0.44) | TDP1KDM4EDUSP3MEN1KMT2A | |
| SCHEMBL8946611 | 0.79 | KDM4E (0.54) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL116747 | 0.78 | USP2 (0.53) | TDP1LMNAHSD17B10ALDH1A1USP2 | |
| SCHEMBL28341190 | 0.77 | TDP1 (0.64) | TDP1KDM4ELMNAHSD17B10ALDH1A1 | |
| SCHEMBL27470862 | 0.77 | TDP1 (0.64) | TDP1KDM4EKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL4885377 | 0.75 | TDP1 (0.57) | TDP1KDM4EKMT2AHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981937-B2 | Orthoformic acid esters as pro-fragrances | HENKEL AG & CO. KGAA (DE) | 2018-05-29 | — | — | US | disclosed |
| US-20170349565-A1 | ORTHOFORMIC ACID ESTERS AS PRO-FRAGRANCES | HENKEL AG & CO. KGAA (DE) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349565-A1 | ORTHOFORMIC ACID ESTERS AS PRO-FRAGRANCES | FAAH, NISCH, ELOVL6 | TDP1 1924/4885KDM4E 2361/4885DUSP3 4247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.