Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28298668 | 0.70 | CALM1 (0.50) | CALM1LTA4HACHENOS1NOS2 | |
| SCHEMBL2045801 | 0.69 | CALM1 (0.55) | CALM1LTA4H | |
| SCHEMBL1829354 | 0.69 | CALM1 (0.55) | CALM1LTA4HALDH1A1HPGD | |
| SCHEMBL2973782 | 0.68 | CALM1 (0.61) | CALM1TSHRLTA4HTP53KDM4E | |
| SCHEMBL6586984 | 0.67 | CALM1 (0.52) | CALM1LTA4H | |
| SCHEMBL1829180 | 0.67 | CALM1 (0.52) | CALM1LTA4H | |
| SCHEMBL19814583 | 0.67 | CALM1 (0.52) | CALM1TSHRSMN1; SMN2LTA4HTP53 | |
| SCHEMBL2051544 | 0.67 | CALM1 (0.52) | CALM1LTA4H | |
| SCHEMBL1591329 | 0.67 | KDM4E (0.65) | ACHEKDM4EHTT | |
| SCHEMBL70870 | 0.67 | KDM4E (0.65) | ACHEKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464284-B1 | MICROBIOCIDAL THIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-10-21 | — | — | EP | disclosed |
| US-20200277288-A1 | Microbiocidal Thiazole Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-09-03 | — | — | US | disclosed |
| US-10662182-B2 | Microbiocidal thiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-26 | — | — | US | disclosed |
| US-20190330168-A1 | MICROBIOCIDAL THIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-31 | — | — | US | disclosed |
| EP-3464284-A1 | MICROBIOCIDAL THIAZOLE DERIVATIVES | Syngenta Participations AG (CH) | 2019-04-10 | — | — | EP | disclosed |
| WO-2017207362-A1 | MICROBIOCIDAL THIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200277288-A1 | Microbiocidal Thiazole Derivatives | MSR1, CASP1, TLR1 | CALM1 2459/4885TSHR 1276/4885SMN1; SMN2 3529/4885 |
| US-20190330168-A1 | MICROBIOCIDAL THIAZOLE DERIVATIVES | MSR1, CASP1, MPO | CALM1 2556/4885TSHR 1348/4885SMN1; SMN2 3478/4885 |
| US-10662182-B2 | Microbiocidal thiazole derivatives | MSR1, CASP1, MPO | CALM1 2556/4885TSHR 1348/4885SMN1; SMN2 3478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.