Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 4/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11923446 | 0.85 | GNAI3 (0.41) | GNAI3GNAO1GNAI1NCF1KEAP1 | |
| SCHEMBL20113022 | 0.84 | GNAI3 (0.42) | GNAI3GNAO1GNAI1NCF1KEAP1 | |
| SCHEMBL15759102 | 0.83 | GNAI3 (0.51) | GNAI3GNAO1GNAI1NCF1KEAP1 | |
| SCHEMBL11928089 | 0.82 | GNAI3 (0.57) | GNAI3GNAO1GNAI1NCF1 | |
| SCHEMBL26707223 | 0.76 | GNAO1 (0.43) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL18502834 | 0.72 | NCF1 (0.45) | GNAI3GNAO1GNAI1HTR1ANCF1 | |
| SCHEMBL12817476 | 0.72 | GNAI3 (0.57) | GNAI3GNAO1GNAI1CHRM1CHRM2 | |
| SCHEMBL23951464 | 0.71 | NCF1 (0.43) | GNAI3GNAO1GNAI1NCF1 | |
| SCHEMBL8899241 | 0.70 | ALDH1A1 (0.39) | — | |
| SCHEMBL19169454 | 0.68 | NCF1 (0.43) | GNAI3GNAO1GNAI1NCF1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834560-B2 | Compounds | RESPIVERT LTD. (GB) | 2017-12-05 | — | — | US | disclosed |