Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19669647 | 0.89 | ITGB3 (0.63) | ITGB3ITGA2BL3MBTL1 | |
| SCHEMBL2267015 | 0.89 | LMNA (0.52) | ITGB3ITGA2BKDM4EALDH1A1GAA | |
| SCHEMBL17996360 | 0.86 | MAPT (0.52) | ITGB3ITGA2BKDM4EALDH1A1GAA | |
| SCHEMBL19669653 | 0.83 | ITGB3 (0.49) | ITGB3ITGA2BKDM4EALDH1A1GAA | |
| SCHEMBL19669631 | 0.83 | RORC (0.57) | ITGB3ITGA2BKDM4EALDH1A1GAA | |
| SCHEMBL18010773 | 0.82 | MAPT (0.46) | ITGB3ITGA2BKDM4EALDH1A1GAA | |
| SCHEMBL28802275 | 0.81 | ITGB3 (0.54) | ITGB3ITGA2BMAPT | |
| SCHEMBL17996414 | 0.80 | MAPT (0.56) | ITGB3ITGA2BKDM4EALDH1A1GAA | |
| SCHEMBL19669654 | 0.80 | TSHR (0.51) | ITGB3ITGA2BKDM4EALDH1A1GAA | |
| SCHEMBL19669648 | 0.79 | TSHR (0.45) | ITGB3ITGA2BKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834520-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-12-05 | — | — | US | disclosed |