Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19669631 | 0.86 | RORC (0.57) | TSHRALOX15POLBMAPTKDM4E | |
| SCHEMBL17996431 | 0.86 | TP53 (0.53) | TSHRALOX15POLBMAPTKDM4E | |
| SCHEMBL18010766 | 0.85 | TSHR (0.43) | TSHRALOX15POLBMAPTKDM4E | |
| SCHEMBL19669648 | 0.85 | TSHR (0.45) | TSHRALOX15POLBMAPTKDM4E | |
| SCHEMBL19669647 | 0.81 | ITGB3 (0.63) | ITGB3ITGA2B | |
| SCHEMBL19669650 | 0.81 | NOS3 (0.51) | TSHRALOX15POLBMAPTKDM4E | |
| SCHEMBL19669652 | 0.80 | CYP1A2 (0.52) | TSHRPOLBMAPTALDH1A1CYP1A2 | |
| SCHEMBL17996374 | 0.80 | MAPT (0.59) | TSHRALOX15POLBMAPTALDH1A1 | |
| SCHEMBL19669633 | 0.80 | CYP3A4 (0.52) | TSHRPOLBMAPTKDM4ECYP1A2 | |
| SCHEMBL19669656 | 0.80 | ITGB3 (0.54) | MAPTKDM4EALDH1A1GAARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834520-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-12-05 | — | — | US | disclosed |