Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 11/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19365256 | 0.92 | RAF1 (0.37) | RAF1KDM1AMAOAMAOBCHRM2 | |
| SCHEMBL19670137 | 0.92 | ALDH1A1 (0.34) | RAF1KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL19670181 | 0.88 | RAF1 (0.35) | RAF1KDM1AMAOAMAOBCHRM2 | |
| SCHEMBL17624556 | 0.86 | RAF1 (0.37) | RAF1KDM1AMAOAMAOBCHRM2 | |
| SCHEMBL19670135 | 0.80 | MEN1 (0.41) | RAF1KDM1AMAOAMAOBKMT2A | |
| SCHEMBL19365594 | 0.80 | RAF1 (0.35) | RAF1KDM1AMAOAMAOBCHRM2 | |
| SCHEMBL19670425 | 0.80 | KMT2A (0.39) | RAF1KDM1AMAOAMAOBKMT2A | |
| SCHEMBL17655329 | 0.79 | FGFR4 (0.39) | RAF1CA2CA9 | |
| SCHEMBL19670406 | 0.79 | CHRM2 (0.36) | RAF1KDM1AMAOAMAOBCHRM2 | |
| SCHEMBL19670214 | 0.79 | TRPA1 (0.38) | RAF1KDM1AMAOAMAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834558-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-12-05 | — | — | US | disclosed |