SCHEMBL1967519

SCHEMBL1967519

CC(C)c1cccc(S)c1S

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.50
LMNA P02545 3/20 0.50
GABRG2 P18507 2/20 0.50
GABRB3 P28472 2/20 0.50
GABRB2 P47870 2/20 0.50
FAAH O00519 2/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
HPGD P15428 1/20 0.50
TSHR P16473 1/20 0.50
GABRB1 P18505 1/20 0.50
PTGS1 P23219 1/20 0.50
SLC6A2 P23975 1/20 0.50
HTR2C P28335 1/20 0.50
GABRA5 P31644 1/20 0.50
GABRA3 P34903 1/20 0.50
HTR2B P41595 1/20 0.50
GABRA2 P47869 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3191750 0.89 GABRA1 (0.55) GABRA1LMNAGABRG2GABRB3GABRB2
SCHEMBL11302188 0.84 GABRA1 (0.39) GABRA1LMNAGABRG2GABRB3GABRB2
SCHEMBL26049555 0.80 TSHR (0.46) GABRA1LMNAGABRG2GABRB3GABRB2
SCHEMBL19972005 0.78 CYP3A4 (0.44) GABRA1LMNAGABRG2GABRB3GABRB2
SCHEMBL19699398 0.78 GABRA1 (0.44) GABRA1LMNAGABRG2GABRB3GABRB2
SCHEMBL191352 0.78 GABRA1 (0.52) GABRA1LMNAGABRG2GABRB3GABRB2
SCHEMBL29986709 0.78 GABRA1 (0.52) GABRA1LMNAGABRG2GABRB3GABRB2
SCHEMBL22096819 0.77 LMNA (0.48) GABRA1LMNAGABRG2GABRB3GABRB2
SCHEMBL769833 0.77 GABRA1 (0.48) GABRA1LMNAGABRG2GABRB3GABRB2
SCHEMBL1972902 0.77 TSHR (0.52) GABRA1LMNAGABRG2GABRB3GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2334661-B1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS UBE INDUSTRIES (JP) 2017-08-30 EP disclosed
US-8653302-B2 Processes for preparing poly(pentafluorosulfanyl)aromatic compounds UBE INDUSTRIES, LTD. (JP) 2014-02-18 US disclosed
US-20110166392-A1 Processes for Preparing Poly(Pentafluorosulfanyl)Aromatic Compounds UBE INDUSTRIES, LTD. (JP) 2011-07-07 US disclosed
EP-2334661-A1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS Ube Industries, Ltd. (JP) 2011-06-22 EP disclosed
WO-2010033930-A1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS IM&T RESEARCH, INC. (US) 2010-03-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166392-A1 Processes for Preparing Poly(Pentafluorosulfanyl)Aromatic Compounds PFAS, PUF60, FES GABRA1 786/4885LMNA 3219/4885GABRG2 1055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.