SCHEMBL769833

SCHEMBL769833

CC(C)c1cccc(S)c1C(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.48
GABRG2 P18507 2/20 0.48
GABRB3 P28472 2/20 0.48
GABRB2 P47870 2/20 0.48
LMNA P02545 2/20 0.48
FAAH O00519 2/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
HPGD P15428 1/20 0.48
TSHR P16473 1/20 0.48
GABRB1 P18505 1/20 0.48
PTGS1 P23219 1/20 0.48
SLC6A2 P23975 1/20 0.48
HTR2C P28335 1/20 0.48
GABRA5 P31644 1/20 0.48
GABRA3 P34903 1/20 0.48
HTR2B P41595 1/20 0.48
GABRA2 P47869 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL66227 0.84 GABRA1 (0.57) GABRA1GABRG2GABRB3GABRB2LMNA
SCHEMBL8340259 0.84 GABRA1 (0.38) GABRA1GABRG2GABRB3GABRB2LMNA
SCHEMBL9539486 0.82 LMNA (0.50) GABRA1GABRG2GABRB3GABRB2LMNA
SCHEMBL29151002 0.81 GABRA1 (0.55) GABRA1GABRG2GABRB3GABRB2LMNA
Benzene SCHEMBL7864298 0.81 GABRA1 (0.55) GABRA1GABRG2GABRB3GABRB2LMNA
SCHEMBL28509290 0.81 GABRA1 (0.55) GABRA1GABRG2GABRB3GABRB2LMNA
Hydrochloric Acid SCHEMBL27766942 0.81 GABRA1 (0.55) GABRA1GABRG2GABRB3GABRB2LMNA
Hydrogen Sulfide SCHEMBL28223639 0.81 GABRA1 (0.55) GABRA1GABRG2GABRB3GABRB2LMNA
Water SCHEMBL27976303 0.81 GABRA1 (0.55) GABRA1GABRG2GABRB3GABRB2LMNA
SCHEMBL28270678 0.80 LMNA (0.32) GABRA1GABRG2GABRB3GABRB2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109554122-B Curing adhesive for polarizing film, optical film, and image display device 日东电工株式会社 2022-03-01 CN disclosed
CN-109536046-B Curing adhesive for polarizing film, optical film, and image display device 日东电工株式会社 2021-06-11 CN disclosed
CN-106661386-B Method for manufacturing laminated optical film 日东电工株式会社 2020-10-23 CN disclosed
CN-105849598-B Laminated polarizing film, method for producing same, laminated optical film, and image display device 日东电工株式会社 2020-02-07 CN disclosed
US-9884043-B2 RORgammaT inhibitors MERCK SHARP & DOHME CORP. (US) 2018-02-06 US disclosed
US-20170340610-A1 RORgammaT INHIBITORS MERCK SHARP & DOHME LLC 2017-11-30 US disclosed
US-20160213891-A1 Medical Dilation Element ZAMORE, ALAN 2016-07-28 US disclosed
US-9333278-B2 Medical dilation element Medtech Capital Ventures LLC (US) 2016-05-10 US disclosed
US-20120070599-A1 Reduced profile medical balloon element ZAMORE, ALAN 2012-03-22 US disclosed
US-20100249906-A1 REDUCED PROFILE MEDICAL BALLOON ELEMENT ZAMORE ALAN M 2010-09-30 US disclosed
US-7749585-B2 Reduced profile medical balloon element ZAMORE, ALAN 2010-07-06 US disclosed
US-20040093008-A1 Reduced profile medical balloon element ZAMORE, ALAN 2004-05-13 US disclosed
US-4476255-A Photoreactive plastic composition and articles degradable by ultraviolet radiation and a process for their manufacture OWENS-ILLINOIS, INC. (US) 1984-10-09 US disclosed
EP-0050261-A1 Moulding masses stabilized against thermolysis with a low monomer content BAYER AG (DE) 1982-04-28 EP disclosed
US-4264658-A Three-component polymeric coating for glass substrate OWENS-ILLINOIS, INC. (US) 1981-04-28 US disclosed
US-4094756-A Photochemical modification of polymers OWENS-ILLINOIS, INC. (US) 1978-06-13 US disclosed
US-4086373-A Protective polymeric coating for glass substrate OWENS-ILLINOIS, INC. (US) 1978-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170340610-A1 RORgammaT INHIBITORS RORB, RORC, RORA GABRA1 210/4885GABRG2 138/4885GABRB3 206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.