SCHEMBL19675665

SCHEMBL19675665

Cc1ccc2c(c1C)C(C)c1ccccc1-2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.36
HTR7 P34969 1/20 0.35
HTR2B P41595 1/20 0.35
CYP1A2 P05177 2/20 0.34
TSHR P16473 2/20 0.32
CYP2A6 P11509 1/20 0.32
TDP2 O95551 1/20 0.32
NSD2 O96028 1/20 0.32
HSP90AA1 P07900 1/20 0.32
PAX8 Q06710 1/20 0.32
HTR2A P28223 1/20 0.32
POLB P06746 3/20 0.32
PBRM1 Q86U86 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31
CHRM2 P08172 1/20 0.31
HTR1A P08908 1/20 0.31
ADRA2A P08913 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD1 P21728 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1871454 0.81 GPR3 (0.34) GPR3HTR7HTR2BHTR2APOLB
SCHEMBL6292515 0.81 GPR3 (0.34) GPR3HTR7HTR2BHTR2APOLB
SCHEMBL29145678 0.81 HTR2A (0.36) GPR3HTR2BCYP1A2TSHRCYP2A6
SCHEMBL31338566 0.80 GPR3 (0.39) GPR3HTR7HTR2BTSHRHTR2A
SCHEMBL358532 0.80 GPR3 (0.39) GPR3HTR7HTR2BTSHRHTR2A
SCHEMBL17515010 0.79 HTR2B (0.36) GPR3HTR7HTR2BCYP1A2TSHR
SCHEMBL14119375 0.79 ALDH1A1 (0.34) GPR3HTR7HTR2BPBRM1NPC1
SCHEMBL2130008 0.79 HTR7 (0.35) GPR3HTR7HTR2BPOLBDRD2
Methyl Alcohol SCHEMBL14815699 0.77 ALDH1A1 (0.38) GPR3HTR7HTR2BPOLBPBRM1
SCHEMBL616348 0.76 PTPRC (0.39) HTR7CYP1A2TDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3252064-A1 METALLOCENE COMPOUND LG Chem, Ltd. (KR) 2017-12-06 EP disclosed