SCHEMBL616348

SCHEMBL616348

COc1ccccc1-c1ccc2c(c1C)C(C)c1ccccc1-2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.39
PTPN1 P18031 1/20 0.39
APP P05067 1/20 0.39
ALDH1A1 P00352 2/20 0.37
HTR7 P34969 6/20 0.36
MEN1 O00255 1/20 0.36
USP2 O75604 1/20 0.36
KMT2A Q03164 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
AKR1C3 P42330 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14119375 0.78 ALDH1A1 (0.34) ALDH1A1HTR7RAB9A
SCHEMBL19675665 0.76 GPR3 (0.36) ALDH1A1HTR7MEN1KMT2ACYP1A2
SCHEMBL1871454 0.73 GPR3 (0.34) ALDH1A1HTR7
SCHEMBL28014118 0.73 HTR7 (0.36) ALDH1A1HTR7CYP3A4
SCHEMBL6292515 0.73 GPR3 (0.34) HTR7
SCHEMBL14118291 0.73 CA1 (0.55) APPALDH1A1HTR7CA12CA1
SCHEMBL5556086 0.73 HTR7 (0.32) HTR7
SCHEMBL2130008 0.71 HTR7 (0.35) HTR7MEN1KMT2A
SCHEMBL301996 0.71 CA1 (0.71) APPALDH1A1HTR7MEN1USP2
SCHEMBL29429633 0.71 CA1 (0.71) APPALDH1A1HTR7MEN1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2324067-B1 ETHYLENE COPOLYMER AND A METHOD OF PREPARING THE SAME SABIC SK NEXLENE COMPANY PTE LTD (SG) 2018-04-25 EP disclosed
EP-2326654-B1 TRANSITION METAL CATALYTIC SYSTEMS AND METHODS FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE AND ALPHA- OLEFINS USING THE SAME. SK INNOVATION CO LTD (KR) 2013-03-20 EP disclosed
US-8232359-B2 Process for preparing ethylene homopolymers or copolymers of ethylene with α-olefin by using the transition metal compound SK INNOVATION CO., LTD. (KR) 2012-07-31 US disclosed
US-20120041149-A1 ETHYLENE COPOLYMER AND A METHOD OF PREPARING THE SAME SK INNOVATION CO., LTD. (KR) 2012-02-16 US disclosed
US-20110319576-A1 PROCESS FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE WITH ALPHA-OLEFIN BY USING THE TRANSITION METAL COMPOUND SK ENERGY CO., LTD. (KR) 2011-12-29 US disclosed
US-8067511-B2 Ethylene copolymer and a method of preparing the same SK INNOVATION CO., LTD. (KR) 2011-11-29 US disclosed
EP-2326654-A2 TRANSITION METAL CATALYTIC SYSTEMS AND METHODS FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE AND - OLEFINS USING THE SAME. SK Energy Co., Ltd. (KR) 2011-06-01 EP disclosed
EP-2324067-A2 ETHYLENE COPOLYMER AND A METHOD OF PREPARING THE SAME SK Energy Co., Ltd. (KR) 2011-05-25 EP disclosed
US-20110098426-A1 TRANSITION METAL CATALYTIC SYSTEMS AND METHODS FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF THE ETHYLENE AND a-OLEFINS USING THE SAME SK ENERGY CO., LTD. (KR) 2011-04-28 US disclosed
US-7928173-B2 Transition metal catalytic systems and methods for preparing ethylene homopolymers or copolymers of ethylene and α-olefins using the same SK ENERGY CO., LTD. (KR) 2011-04-19 US disclosed
US-20100120981-A1 ETHYLENE COPOLYMER AND A METHOD OF PREPARING THE SAME SABIC SK NEXLENE COMPANY PTE. LTD. (SG) 2010-05-13 US disclosed
US-20100081776-A1 TRANSITION METAL CATALYTIC SYSTEMS AND METHODS FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE AND a-OLEFINS USING THE SAME SABIC SK NEXLENE COMPANY PTE. LTD. (SG) 2010-04-01 US disclosed
WO-2010036025-A2 TRANSITION METAL CATALYTIC SYSTEMS AND METHODS FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE AND α- OLEFINS USING THE SAME. SK ENERGY CO., LTD. (KR) 2010-04-01 WO disclosed
WO-2010030145-A2 ETHYLENE COPOLYMER AND A METHOD OF PREPARING THE SAME SK ENERGY CO., LTD. (KR) 2010-03-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100081776-A1 TRANSITION METAL CATALYTIC SYSTEMS AND METHODS FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE AND a-OLEFINS USING THE SAME ESR1, AOC3, PPOX PTPRC 3336/4885PTPN1 3907/4885APP 2345/4885
US-20110098426-A1 TRANSITION METAL CATALYTIC SYSTEMS AND METHODS FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF THE ETHYLENE AND a-OLEFINS USING THE SAME ESR1, AOC3, AOC2 PTPRC 3212/4885PTPN1 4032/4885APP 2302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.