SCHEMBL1967951

SCHEMBL1967951

Nc1ccc(NC(=O)C(=O)O)cc1

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.64
RAB9A P51151 2/20 0.64
PTPN11 Q06124 2/20 0.61
PTPN1 P18031 1/20 0.61
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
LMNA P02545 1/20 0.57
POLB P06746 1/20 0.57
PKM P14618 1/20 0.57
APEX1 P27695 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
GPR35 Q9HC97 1/20 0.54
PTPN6 P29350 1/20 0.50
CYP19A1 P11511 2/20 0.49
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2495334 0.94 PTPN11 (0.71) MAPTRAB9APTPN11PTPN1MEN1
SCHEMBL10495628 0.88 PTPN11 (0.74) PTPN11PTPN1MEN1KMT2AGPR35
SCHEMBL10690966 0.83 MAPT (0.59) MAPTRAB9APTPN11PTPN1MEN1
SCHEMBL3038302 0.81 MAPT (0.70) MAPTRAB9AMEN1KMT2ALMNA
Hydrochloric Acid SCHEMBL23629626 0.79 MAPT (0.67) MAPTRAB9AMEN1KMT2ALMNA
SCHEMBL6394183 0.79 ALDH1A1 (0.63) MAPTPTPN11PTPN1MEN1KMT2A
SCHEMBL8772924 0.78 RAB9A (1.00) MAPTRAB9AMEN1KMT2ALMNA
SCHEMBL616739 0.78 PTPN11 (0.75) RAB9APTPN11PTPN1MEN1KMT2A
SCHEMBL1504197 0.77 PTPN11 (0.61) PTPN11PTPN1MEN1KMT2ALMNA
SCHEMBL3542766 0.77 PTPN1 (0.61) PTPN11PTPN1MEN1KMT2AGPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0733113-B1 INFLUENZA VACCINE VLAAMS INTERUNIV INST BIOTECH (BE) 2007-05-02 EP claimed
US-20030129197-A1 Influenza vaccine VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE 2003-07-10 US claimed
EP-0733113-A1 INFLUENZA VACCINE RIJKSUNIVERSITEIT GENT (BE) 1996-09-25 EP claimed
WO-1995018861-A1 INFLUENZA VACCINE VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE (BE) 1995-07-13 WO claimed
US-12146891-B2 United states systems and methods for fluid and component handling LABRADOR DIAGNOSTICS LLC (US) 2024-11-19 US disclosed
US-12085583-B2 Systems and methods for multi-analysis LABRADOR DIAGNOSTICS LLC (US) 2024-09-10 US disclosed
EP-4130273-B1 PRODUCTION OF HETEROLOGOUS POLYPEPTIDES IN MICROALGAE, MICROALGAL EXTRACELLULAR BODIES, COMPOSITIONS, AND METHODS OF MAKING AND USES THEREOF SANOFI VACCINE TECH S A S (FR) 2024-06-12 EP disclosed
EP-4220120-A2 SYSTEMS AND METHODS FOR MULTI-ANALYSIS Labrador Diagnostics LLC (US) 2023-08-02 EP disclosed
EP-4130273-A1 PRODUCTION OF HETEROLOGOUS POLYPEPTIDES IN MICROALGAE, MICROALGAL EXTRACELLULAR BODIES, COMPOSITIONS, AND METHODS OF MAKING AND USES THEREOF Sanofi Vaccine Technologies, S.A.S. (FR) 2023-02-08 EP disclosed
EP-2956754-B1 SYSTEMS AND METHODS FOR MULTI-ANALYSIS LABRADOR DIAGNOSTICS LLC (US) 2023-01-11 EP disclosed
US-11524299-B2 Systems and methods for fluid handling LABRADOR DIAGNOSTICS LLC (US) 2022-12-13 US disclosed
CN-114994342-A System and method for multivariate analysis 赛拉诺斯知识产权有限责任公司 2022-09-02 CN disclosed
US-4595761-A Dicarboxylic acid azomethines and high glass transition temperature polyester products produced therefrom FORD MOTOR COMPANY (US) 1986-06-17 US disclosed
EP-0167858-A1 Fiber-reactive disazo compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-01-15 EP disclosed
US-4540776-A Reactive fluorotriazinylaminonaphthotriazolyphenylazopyridone or pyrimidone dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1985-09-10 US disclosed
US-4474697-A DYEING COTTON BAYER AKTIENGESELSCHAFT (DE) 1984-10-02 US disclosed
EP-0012349-B1 PROCESS FOR PRODUCING PHTHALOCYANINE REACTIVE DYESTUFFS BAYER AG (DE) 1981-11-04 EP disclosed
US-4246174-A Process for the preparation of phthalocyanine reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1981-01-20 US disclosed
EP-0012349-A2 Process for producing phthalocyanine reactive dyestuffs BAYER AG (DE) 1980-06-25 EP disclosed
US-4139530-A CATIONIC DYES BAYER AKTIENGESELLSCHAFT (DE) 1979-02-13 US disclosed