Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPP3CA | Q08209 | 6/20 | 0.69 |
| ▸ | ABCB1 | P08183 | 11/20 | 0.69 |
| ▸ | PPIA | P62937 | 4/20 | 0.69 |
| ▸ | PPID | Q08752 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.69 |
| ▸ | GMNN | O75496 | 1/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.69 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | RARB | P10826 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.69 |
| ▸ | TACR2 | P21452 | 1/20 | 0.69 |
| ▸ | PPIB | P23284 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21582611 | 1.00 | PPP3CA (0.69) | PPP3CAABCB1PPIAPPIDMEN1 | |
| SCHEMBL9979458 | 0.90 | PPP3CA (0.78) | PPP3CAABCB1PPIAPPIDMEN1 | |
| SCHEMBL1081330 | 0.90 | PPP3CA (0.78) | PPP3CAABCB1PPIAPPIDMEN1 | |
| SCHEMBL9979538 | 0.90 | PPP3CA (0.63) | PPP3CAABCB1PPIAPPIDMEN1 | |
| SCHEMBL19680000 | 0.89 | PPP3CA (0.80) | PPP3CAABCB1PPIAPPIDMEN1 | |
| SCHEMBL9979647 | 0.89 | PPP3CA (0.80) | PPP3CAABCB1PPIAPPIDMEN1 | |
| SCHEMBL9979536 | 0.88 | ABCB1 (0.80) | PPP3CAABCB1PPIAPPIDMEN1 | |
| SCHEMBL19680002 | 0.88 | ABCB1 (0.80) | PPP3CAABCB1PPIAPPIDMEN1 | |
| SCHEMBL21582623 | 0.88 | ABCB1 (0.80) | PPP3CAABCB1PPIAPPIDMEN1 | |
| SCHEMBL9979652 | 0.87 | ABCB1 (0.68) | PPP3CAABCB1PPIAPPIDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349632-A1 | QUINOLIUM CONJUGATES OF CYCLOSPORIN | UCL BUSINESS PLC (GB) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349632-A1 | QUINOLIUM CONJUGATES OF CYCLOSPORIN | SHMT2, CS, SQOR | PPP3CA 345/4885ABCB1 109/4885PPIA 190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.