Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.34 |
| ▸ | RELA | Q04206 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19681508 | 0.82 | GPR84 (0.36) | GPR84L3MBTL1KDM5AKDM4CPHF8 | |
| SCHEMBL19677890 | 0.80 | GPR84 (0.42) | GPR84L3MBTL1KDM5AKDM4CPHF8 | |
| SCHEMBL25963472 | 0.78 | GPR84 (0.41) | GPR84L3MBTL1KDM5AKDM4CPHF8 | |
| SCHEMBL25963617 | 0.78 | GPR84 (0.41) | GPR84L3MBTL1KDM5AKDM4CPHF8 | |
| SCHEMBL16500388 | 0.78 | GGPS1 (0.44) | GPR84DNM1L3MBTL1KDM5AKDM4C | |
| SCHEMBL19677889 | 0.77 | DNM1 (0.48) | GPR84DNM1L3MBTL1PSMD14PLA2G1B | |
| SCHEMBL19681580 | 0.75 | GPR84 (0.39) | GPR84L3MBTL1PSMD14PLA2G1BMMP2 | |
| SCHEMBL5412524 | 0.74 | DNM1 (0.48) | GPR84DNM1L3MBTL1PSMD14PLA2G1B | |
| SCHEMBL5406861 | 0.74 | DNM1 (0.48) | GPR84DNM1L3MBTL1PSMD14PLA2G1B | |
| SCHEMBL5408876 | 0.74 | DNM1 (0.48) | GPR84DNM1L3MBTL1PSMD14PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349543-A1 | CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349543-A1 | CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS | ABHD16A, AARS1, CFTR | GPR84 684/4885DNM1 700/4885RELA 2793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.