Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12321558 | 0.80 | PDK1 (0.45) | SLC6A4KMT2ARAPGEF4MEN1NPC1 | |
| SCHEMBL30122263 | 0.80 | PDK1 (0.45) | SLC6A4KMT2ARAPGEF4MEN1NPC1 | |
| SCHEMBL13754322 | 0.79 | GAA (0.43) | CYP3A4KDM4ESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19681876 | 0.78 | ESR1 (0.52) | KDM4EHIF1ASRD5A2KMT2AMEN1 | |
| SCHEMBL19681872 | 0.77 | MAOA (0.40) | CYP3A4KDM4ECYP2C19KMT2AMEN1 | |
| SCHEMBL5129791 | 0.77 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL20132403 | 0.76 | CYP3A4 (0.53) | CYP3A4KDM4ECYP2C19HIF1ASLC5A1 | |
| SCHEMBL14397402 | 0.75 | CYP3A4 (0.47) | CYP3A4KDM4ESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9695488 | 0.74 | CYP3A4 (0.50) | CYP3A4KDM4ESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14432483 | 0.74 | SLC6A4 (0.46) | KDM4ESLC6A2SLC6A4SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3901162-A1 | GLUCOCORTICOID RECEPTOR AGONIST AND IMMUNOCONJUGATES THEREOF | AbbVie Inc. (US) | 2021-10-27 | — | — | EP | disclosed |
| WO-2017207776-A1 | SYSTEM FOR DISPENSING A COSMETIC PRODUCT | L'OREAL (FR) | 2017-12-07 | — | — | WO | disclosed |