Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19681869 | 0.88 | MEN1 (0.41) | MAOAMAOBPTGDR2HTTNPSR1 | |
| SCHEMBL19681873 | 0.79 | L3MBTL1 (0.41) | MAOAMAOBNPSR1RAB9AMEN1 | |
| SCHEMBL20132348 | 0.78 | RAB9A (0.47) | MAOAMAOBPTGDR2HTTDAO | |
| SCHEMBL19681892 | 0.77 | CYP3A4 (0.38) | DAORAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL22602010 | 0.75 | RAB9A (0.47) | MAOAMAOBPTGDR2HTTDAO | |
| SCHEMBL11601101 | 0.74 | ALDH1A1 (0.56) | MAOAMAOBHTTNPSR1DAO | |
| SCHEMBL19681864 | 0.74 | MEN1 (0.47) | HTTNPSR1DAORAB9AMEN1 | |
| SCHEMBL22894334 | 0.73 | MEN1 (0.67) | MAOAMAOBHTTNPSR1RAB9A | |
| SCHEMBL10657873 | 0.73 | MEN1 (0.67) | MAOAMAOBHTTNPSR1RAB9A | |
| SCHEMBL12321558 | 0.72 | PDK1 (0.45) | RAB9AMEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3901162-A1 | GLUCOCORTICOID RECEPTOR AGONIST AND IMMUNOCONJUGATES THEREOF | AbbVie Inc. (US) | 2021-10-27 | — | — | EP | disclosed |
| WO-2017207776-A1 | SYSTEM FOR DISPENSING A COSMETIC PRODUCT | L'OREAL (FR) | 2017-12-07 | — | — | WO | disclosed |