SCHEMBL30122263

SCHEMBL30122263

CNc1cc(C)ccc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK1 Q15118 1/20 0.45
PDK2 Q15119 1/20 0.45
PDK3 Q15120 1/20 0.45
PDK4 Q16654 1/20 0.45
RAB9A P51151 2/20 0.42
NPC1 O15118 1/20 0.42
RAPGEF4 Q8WZA2 2/20 0.41
CLCN2 P51788 1/20 0.39
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39
TAS1R2 Q8TE23 1/20 0.39
MAPT P10636 1/20 0.38
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
KMT2A Q03164 1/20 0.37
HPGD P15428 1/20 0.36
MCL1 Q07820 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2A6 P11509 1/20 0.36
HTR2A P28223 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12321558 1.00 PDK1 (0.45) PDK1PDK2PDK3PDK4RAB9A
SCHEMBL5768693 0.81 RAB9A (0.47) RAB9ANPC1RAPGEF4TAS1R3TAS1R1
SCHEMBL19681892 0.80 CYP3A4 (0.38) RAB9ANPC1RAPGEF4MAPTMEN1
SCHEMBL5360509 0.79 PDK1 (0.47) PDK1PDK2PDK3PDK4RAB9A
SCHEMBL11404618 0.79 PDK1 (0.47) PDK1PDK2PDK3PDK4RAB9A
SCHEMBL3231268 0.79 ALDH1A1 (0.50) PDK1PDK2PDK3PDK4RAB9A
SCHEMBL19681873 0.78 L3MBTL1 (0.41) RAB9ANPC1RAPGEF4MAPTMEN1
SCHEMBL1679559 0.78 RAPGEF4 (0.52) PDK1PDK2PDK3PDK4RAPGEF4
Hydrochloric Acid SCHEMBL3619887 0.77 ALDH1A1 (0.48) PDK1PDK2PDK3PDK4RAB9A
SCHEMBL12889181 0.77 HPGD (0.45) RAPGEF4MEN1ALDH1A1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112409186-B Method for synthesizing N-methylaniline in water 南京理工大学 2022-12-13 CN disclosed