Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.53 |
| ▸ | ACHE | P22303 | 3/20 | 0.53 |
| ▸ | BACE1 | P56817 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16476070 | 1.00 | BCHE (0.53) | BCHEACHEBACE1KDM4ESMN1; SMN2 | |
| SCHEMBL16476071 | 1.00 | BCHE (0.53) | BCHEACHEBACE1KDM4ESMN1; SMN2 | |
| SCHEMBL19683310 | 0.83 | ALDH1A1 (0.58) | BCHEACHEBACE1KDM4ESMN1; SMN2 | |
| SCHEMBL13527050 | 0.83 | ALDH1A1 (0.58) | BCHEACHEBACE1KDM4ESMN1; SMN2 | |
| SCHEMBL13527054 | 0.83 | ALDH1A1 (0.58) | BCHEACHEBACE1KDM4ESMN1; SMN2 | |
| SCHEMBL16252994 | 0.81 | GAA (0.55) | BCHEACHEBACE1KDM4ESMN1; SMN2 | |
| SCHEMBL16479598 | 0.81 | KDM4E (0.51) | BCHEACHEBACE1KDM4ESMN1; SMN2 | |
| SCHEMBL20303637 | 0.80 | KDM4E (0.54) | BCHEACHEBACE1KDM4ESMN1; SMN2 | |
| SCHEMBL21774510 | 0.80 | KDM4E (0.54) | BCHEACHEBACE1KDM4ESMN1; SMN2 | |
| SCHEMBL14568091 | 0.80 | BCHE (0.53) | BCHEACHEBACE1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190211046-A1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | BioVersys AG (CH) | 2019-07-11 | — | — | US | disclosed |
| US-20170349621-A1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | BioVersys AG (CH) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349621-A1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | PROKR1, ARG1, ARG2 | BCHE 2005/4885ACHE 1354/4885BACE1 2901/4885 |
| US-20190211046-A1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | PROKR1, ARG1, ARG2 | BCHE 2005/4885ACHE 1354/4885BACE1 2901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.