Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CCR2 | P41597 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13527050 | 1.00 | ALDH1A1 (0.58) | ALDH1A1KDM4ESMN1; SMN2HRH3BCHE | |
| SCHEMBL13527054 | 1.00 | ALDH1A1 (0.58) | ALDH1A1KDM4ESMN1; SMN2HRH3BCHE | |
| SCHEMBL13726519 | 0.84 | ALDH1A1 (0.61) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPT | |
| SCHEMBL16479598 | 0.84 | KDM4E (0.51) | ALDH1A1KDM4ESMN1; SMN2HRH3BCHE | |
| SCHEMBL20303637 | 0.83 | KDM4E (0.54) | ALDH1A1KDM4ESMN1; SMN2HRH3BCHE | |
| SCHEMBL21774510 | 0.83 | KDM4E (0.54) | ALDH1A1KDM4ESMN1; SMN2HRH3BCHE | |
| SCHEMBL16476071 | 0.83 | BCHE (0.53) | ALDH1A1KDM4ESMN1; SMN2HRH3BCHE | |
| SCHEMBL14568091 | 0.83 | BCHE (0.53) | ALDH1A1KDM4ESMN1; SMN2HRH3BCHE | |
| SCHEMBL16476070 | 0.83 | BCHE (0.53) | ALDH1A1KDM4ESMN1; SMN2HRH3BCHE | |
| SCHEMBL19683151 | 0.83 | BCHE (0.53) | ALDH1A1KDM4ESMN1; SMN2HRH3BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190211046-A1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | BioVersys AG (CH) | 2019-07-11 | — | — | US | disclosed |
| US-20170349621-A1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | BioVersys AG (CH) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349621-A1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | PROKR1, ARG1, ARG2 | ALDH1A1 1300/4885KDM4E 3922/4885SMN1; SMN2 4358/4885 |
| US-20190211046-A1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | PROKR1, ARG1, ARG2 | ALDH1A1 1300/4885KDM4E 3922/4885SMN1; SMN2 4358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.