Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19683339 | 0.94 | CYP26B1 (0.33) | CYP26B1CYP26A1PLA2G2APLA2G4ATNKS | |
| SCHEMBL19683342 | 0.94 | CYP26B1 (0.39) | CYP26B1CYP26A1PLA2G2APLA2G4ATNKS | |
| SCHEMBL19683432 | 0.93 | CYP26B1 (0.41) | CYP26B1CYP26A1PLA2G2APLA2G4ATNKS | |
| SCHEMBL31672329 | 0.85 | CYP1A1 (0.38) | CYP26B1CYP26A1ALDH1A1MAPTABCG2 | |
| SCHEMBL19683341 | 0.85 | CYP1A1 (0.38) | CYP26B1CYP26A1ALDH1A1MAPTABCG2 | |
| SCHEMBL26725247 | 0.83 | ALOX5 (0.43) | CYP26B1CYP26A1ALDH1A1MAPTKDM4E | |
| SCHEMBL19683540 | 0.82 | MAOB (0.36) | ALDH1A1MAPTABCG2ABCB1KDM4E | |
| SCHEMBL21342591 | 0.81 | TP53 (0.34) | TNKSALDH1A1MAPTABCG2PGR | |
| SCHEMBL31692104 | 0.80 | CYP1A1 (0.39) | CYP26B1CYP26A1ALDH1A1MAPTABCG2 | |
| SCHEMBL20208836 | 0.80 | GPR84 (0.33) | ALDH1A1MAPTTP53THRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017210072-A1 | ELECTROACTIVE COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2017-12-07 | — | — | WO | disclosed |