Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | GABRE | P78334 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.32 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.32 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19683316 | 0.94 | CYP26B1 (0.36) | CYP26B1CYP26A1PLA2G2APLA2G4AALDH1A1 | |
| SCHEMBL19683342 | 0.88 | CYP26B1 (0.39) | CYP26B1CYP26A1PLA2G2APLA2G4AALDH1A1 | |
| SCHEMBL19683432 | 0.87 | CYP26B1 (0.41) | CYP26B1CYP26A1PLA2G2APLA2G4AALDH1A1 | |
| SCHEMBL31672329 | 0.80 | CYP1A1 (0.38) | CYP26B1CYP26A1ALDH1A1MAPTABCG2 | |
| SCHEMBL19683341 | 0.80 | CYP1A1 (0.38) | CYP26B1CYP26A1ALDH1A1MAPTABCG2 | |
| SCHEMBL26725247 | 0.78 | ALOX5 (0.43) | CYP26B1CYP26A1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL19683540 | 0.77 | MAOB (0.36) | ALDH1A1MAPTABCG2ABCB1SMN1; SMN2 | |
| SCHEMBL21342591 | 0.76 | TP53 (0.34) | ALDH1A1MAPTTNKSABCG2THRB | |
| SCHEMBL31692104 | 0.75 | CYP1A1 (0.39) | CYP26B1CYP26A1ALDH1A1MAPTABCG2 | |
| SCHEMBL20208836 | 0.75 | GPR84 (0.33) | ALDH1A1MAPTTHRBSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017210072-A1 | ELECTROACTIVE COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2017-12-07 | — | — | WO | disclosed |