SCHEMBL19683392

SCHEMBL19683392

CC(C)(C)c1cccc(Nc2cccc(-c3ccccc3)c2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.56
SYK P43405 2/20 0.52
KIF11 P52732 2/20 0.51
RXRA P19793 1/20 0.50
RXRB P28702 1/20 0.50
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.47
AR P10275 1/20 0.47
MAPT P10636 1/20 0.47
KMT2A Q03164 1/20 0.47
KCNK18 Q7Z418 1/20 0.45
MGLL Q99685 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
CNR1 P21554 1/20 0.43
SIRT2 Q8IXJ6 1/20 0.43
SIRT1 Q96EB6 1/20 0.43
GRM4 Q14833 1/20 0.43
IDH2 P48735 1/20 0.42
STK10 O94804 1/20 0.42
SLK Q9H2G2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22132725 0.93 ABCG2 (0.53) ABCG2SYKKIF11RXRARXRB
SCHEMBL24732154 0.93 ABCG2 (0.52) ABCG2SYKKIF11RXRARXRB
SCHEMBL19668831 0.91 ABCG2 (0.55) ABCG2SYKKIF11RXRARXRB
SCHEMBL29244192 0.91 SYK (0.51) ABCG2SYKKIF11RXRARXRB
Hydrochloric Acid SCHEMBL28681818 0.90 ABCG2 (0.53) ABCG2SYKKIF11RXRARXRB
Hydrochloric Acid SCHEMBL29706031 0.90 ABCG2 (0.53) ABCG2SYKKIF11RXRARXRB
SCHEMBL3398439 0.89 ALDH1A1 (0.60) ABCG2KIF11MEN1ALDH1A1AR
SCHEMBL22915687 0.88 CNR1 (0.52) ABCG2SYKKIF11RXRARXRB
SCHEMBL20193326 0.88 CNR1 (0.52) ABCG2SYKKIF11MEN1ALDH1A1
SCHEMBL21625856 0.87 KIF11 (0.54) ABCG2KIF11MEN1ALDH1A1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304595-A1 Electroactive Compounds LG CHEM, LTD. (KR) 2025-10-02 US disclosed
US-20220389027-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2022-12-08 US disclosed
CN-109153684-B Electroactive compounds 株式会社LG化学 2021-12-21 CN disclosed
WO-2020122671-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2020-06-18 WO disclosed
WO-2017210072-A1 ELECTROACTIVE COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2017-12-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304595-A1 Electroactive Compounds NAT1, NES, SULT1E1 ABCG2 1310/4885SYK 4881/4885KIF11 3995/4885
US-20220389027-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, CCNA1, CRY2 ABCG2 3665/4885SYK 2951/4885KIF11 2409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.