SCHEMBL19683670

SCHEMBL19683670

CC1C=CC(N(c2ccccc2)c2ccc(-c3cc4c(ccc5ccc6cc(-c7ccc(N(c8ccccc8)c8ccccc8)cc7)oc6c54)o3)cc2)=CC1

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.33
TNKS O95271 1/20 0.32
CDK1 P06493 1/20 0.32
MAPKAPK2 P49137 1/20 0.32
ABCG2 Q9UNQ0 2/20 0.31
CYP1A1 P04798 1/20 0.31
CYP1A2 P05177 1/20 0.31
FYN P06241 1/20 0.31
MAPK3 P27361 1/20 0.31
AHR P35869 1/20 0.31
PAX8 Q06710 1/20 0.31
MAOB P27338 2/20 0.31
MAOA P21397 1/20 0.31
PLA2G2A P14555 1/20 0.31
PLA2G4A P47712 1/20 0.31
CCNC P24863 1/20 0.31
CDK8 P49336 1/20 0.31
CYP19A1 P11511 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19683305 0.85 PAX8 (0.41) APPTNKSABCG2CYP1A1CYP1A2
SCHEMBL19683308 0.78 CYP1A1 (0.36) APPTNKSABCG2CYP1A1CYP1A2
SCHEMBL22136235 0.75 ALDH1A1 (0.35) APPCYP1A2L3MBTL1
SCHEMBL18523979 0.74 ALDH1A1 (0.38) APPCYP1A2L3MBTL1
SCHEMBL19048808 0.73 CYP1A2 (0.32) CYP1A2L3MBTL1
SCHEMBL29345361 0.73 GPR88 (0.32) CYP1A2L3MBTL1
SCHEMBL18723806 0.72
SCHEMBL19942830 0.72
SCHEMBL19593121 0.71 ALDH1A1 (0.32) CYP1A2L3MBTL1
SCHEMBL13968324 0.71 ALDH1A1 (0.32) CYP1A2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017210072-A1 ELECTROACTIVE COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2017-12-07 WO disclosed