Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.32 |
| ▸ | KIT | P10721 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.30 |
| ▸ | HPGD | P15428 | 3/20 | 0.30 |
| ▸ | RECQL | P46063 | 3/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.30 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20683148 | 1.00 | MET (0.32) | METKITFGFR1SRCKDR | |
| SCHEMBL19661053 | 0.84 | ADRA1D (0.31) | ADRA1A | |
| SCHEMBL20883322 | 0.84 | SLC6A2 (0.34) | ADRA1AHSD17B10KDM4ETP53ALDH1A1 | |
| SCHEMBL19683582 | 0.70 | ESR1 (0.33) | — | |
| SCHEMBL20883313 | 0.69 | SLC6A2 (0.33) | HSD17B10KDM4EALDH1A1L3MBTL1POLB | |
| SCHEMBL19683581 | 0.65 | KDM4E (0.36) | MAPTMAPK1KDM4E | |
| SCHEMBL13079212 | 0.63 | MAOA (0.37) | — | |
| SCHEMBL29438009 | 0.61 | ESR1 (0.34) | METKITFGFR1SRCKDR | |
| SCHEMBL9900562 | 0.61 | ESR1 (0.34) | METKITFGFR1SRCKDR | |
| SCHEMBL9904807 | 0.60 | MAOA (0.33) | METKITFGFR1SRCKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017207519-A1 | PROCESS FOR OBTAINING 3,14-DIACETYLOXYMORPHONE FROM ORIPAVINE | ALCALIBER INVESTIGACIÓN DESARROLLO E INNOVACIÓN, S.L. (ES) | 2017-12-07 | — | — | WO | disclosed |