Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15489500 | 0.84 | RIPK1 (0.37) | RIPK1 | |
| SCHEMBL18893576 | 0.84 | RIPK1 (0.37) | RIPK1 | |
| SCHEMBL19118274 | 0.79 | MEN1 (0.42) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL1517434 | 0.77 | MEN1 (0.36) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL23867079 | 0.75 | LMNA (0.62) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL1436756 | 0.75 | MEN1 (0.39) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL11763336 | 0.75 | ALOX15 (0.41) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL17314985 | 0.75 | ACE2 (0.42) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL1426138 | 0.75 | TSHR (0.46) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL11688603 | 0.75 | MEN1 (0.35) | MEN1CYP3A4ALOX15KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017210685-A1 | PYRADAZINONE DERIVATIVES AND THE COMPOSITIONS AND METHODS OF TREATMENT REGARDING THE SAME | An2H Discovery Limited (IE) | 2017-12-07 | — | — | WO | disclosed |