Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 3/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18914159 | 0.93 | MAPT (0.48) | ALDH1A1MAPTHPGDHTTHSP90AA1 | |
| SCHEMBL22176362 | 0.86 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDHTTHSP90AA1 | |
| SCHEMBL22176383 | 0.86 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDHTTHSP90AA1 | |
| SCHEMBL24468015 | 0.85 | SMN1; SMN2 (0.48) | ALDH1A1MAPTHPGDHTTHSP90AA1 | |
| SCHEMBL22176379 | 0.85 | MAPT (0.47) | ALDH1A1MAPTHPGDHTTHSP90AA1 | |
| SCHEMBL29629519 | 0.85 | SMN1; SMN2 (0.48) | ALDH1A1MAPTHPGDHTTHSP90AA1 | |
| Hydrochloric Acid SCHEMBL22164206 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDHTTHSP90AA1 | |
| SCHEMBL22176051 | 0.85 | L3MBTL4 (0.48) | ALDH1A1MAPTHPGDHTTHSP90AA1 | |
| Hydrochloric Acid SCHEMBL22164245 | 0.85 | MAPT (0.47) | ALDH1A1MAPTHPGDHTTHSP90AA1 | |
| SCHEMBL19684887 | 0.84 | SMPD1 (0.50) | ALDH1A1MAPTFAAHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170348313-A1 | SUBSTITUTED CARBONUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER INC. (US) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170348313-A1 | SUBSTITUTED CARBONUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS | DUT, NCL, TYMP | ALDH1A1 2669/4885MAPT 3784/4885HPGD 1619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.