Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.35 |
| ▸ | KCNB2 | Q92953 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | NEK2 | P51955 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18937645 | 0.86 | ALDH1A1 (0.41) | MAPTGAAALDH1A1TSHRTP53 | |
| SCHEMBL8924902 | 0.80 | MAPT (0.61) | MAPTGAAALDH1A1TSHRTP53 | |
| SCHEMBL29365484 | 0.80 | MAPT (0.61) | MAPTGAAALDH1A1TSHRTP53 | |
| SCHEMBL8578207 | 0.78 | GAA (0.59) | MAPTGAAALDH1A1TSHRTP53 | |
| SCHEMBL2267690 | 0.77 | MAPT (0.57) | MAPTGAAALDH1A1TSHRTP53 | |
| SCHEMBL2491643 | 0.75 | MAPT (0.67) | MAPTGAAALDH1A1TSHRTP53 | |
| SCHEMBL27823469 | 0.75 | ALDH1A1 (0.60) | MAPTGAAALDH1A1TSHRTP53 | |
| SCHEMBL23836627 | 0.74 | MAPT (0.46) | MAPTGAAALDH1A1TSHRTP53 | |
| SCHEMBL9626470 | 0.74 | MEN1 (0.45) | MAPTGAAALDH1A1TSHRTP53 | |
| SCHEMBL23940172 | 0.73 | MAPT (0.53) | MAPTGAAALDH1A1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017210694-A1 | TRIAZOLE BENZAMIDE DERIVATIVES AND THE COMPOSITIONS AND METHODS OF TREATMENT REGARDING THE SAME | An2H Discovery Limited (IE) | 2017-12-07 | — | — | WO | disclosed |