SCHEMBL19685801

SCHEMBL19685801

Cc1cc(=O)c2ccc(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)cc2o1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.45
CYP1B1 Q16678 5/20 0.45
CYP1A1 P04798 4/20 0.45
TNKS O95271 3/20 0.44
ACHE P22303 2/20 0.44
PLA2G2A P14555 4/20 0.42
PLA2G4A P47712 4/20 0.42
QPCT Q16769 1/20 0.41
CYP19A1 P11511 2/20 0.41
MAOB P27338 4/20 0.40
PARP1 P09874 1/20 0.40
TNKS2 Q9H2K2 1/20 0.40
PARP2 Q9UGN5 1/20 0.40
CA12 O43570 1/20 0.40
AKR1B10 O60218 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
ABCB1 P08183 1/20 0.40
CALM1 P0DP23 1/20 0.40
HSD17B1 P14061 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19685796 0.90 ACHE (0.47) CYP1A2CYP1B1CYP1A1TNKSACHE
SCHEMBL19685958 0.89 ACHE (0.53) CYP1A2CYP1B1CYP1A1TNKSACHE
SCHEMBL19685957 0.81 ACHE (0.57) CYP1A2CYP1B1CYP1A1TNKSACHE
SCHEMBL20276662 0.81 HCRTR1 (0.48) ACHEMAOAXDHTDP1MEN1
SCHEMBL10110694 0.80 MMP12 (0.41) CYP1A2PLA2G2APLA2G4ATDP1MEN1
SCHEMBL16850528 0.79 PRKDC (0.40) CYP1A2PLA2G2APLA2G4ATDP1MEN1
SCHEMBL19445011 0.79 PRKDC (0.40) CYP1A2PLA2G2APLA2G4ATDP1MEN1
SCHEMBL19685695 0.78 ACHE (0.38) CYP1A2CYP1B1CYP1A1TNKSACHE
SCHEMBL19213258 0.77 ALDH1A1 (0.38) CYP1A2PLA2G2APLA2G4APKMMAOA
SCHEMBL16850530 0.77 PRKDC (0.41) CYP1A2PLA2G2APLA2G4ATDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-14 US disclosed
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same CYC1, CCNA1, CYCS CYP1A2 902/4885CYP1B1 112/4885CYP1A1 102/4885
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS CYP1A2 902/4885CYP1B1 112/4885CYP1A1 102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.