SCHEMBL19685802

SCHEMBL19685802

O=c1occc2ccc(-n3c4ccc(-c5ccccc5)cc4c4cc(-c5ccccc5)ccc43)cc12

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.38
PIM1 P11309 1/20 0.36
PLG P00747 1/20 0.36
PLAU P00749 1/20 0.36
CTRC Q99895 1/20 0.34
PTPN1 P18031 2/20 0.34
PTPN2 P17706 1/20 0.34
LDHA P00338 2/20 0.33
PRKDC P78527 2/20 0.33
EDNRB P24530 1/20 0.33
EDNRA P25101 1/20 0.33
FAAH O00519 1/20 0.33
MGLL Q99685 1/20 0.33
NR3C1 P04150 1/20 0.33
HSD11B1 P28845 1/20 0.33
TSPO P30536 1/20 0.33
KCNMA1 Q12791 1/20 0.32
NR4A2 P43354 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17358442 0.80 ALDH1A1 (0.41) PGRPIM1PLGPLAULDHA
SCHEMBL19685853 0.79 TNKS2 (0.37) CTRCPTPN1PTPN2EDNRBEDNRA
SCHEMBL20826215 0.78 ESR1 (0.46) PGRPIM1LDHANR3C1TSPO
SCHEMBL11998169 0.78 L3MBTL1 (0.50) LDHAFAAHMGLLNR3C1TSPO
SCHEMBL11998158 0.78 L3MBTL1 (0.50) LDHAFAAHMGLLNR3C1TSPO
SCHEMBL25820471 0.78 L3MBTL1 (0.50) LDHAFAAHMGLLNR3C1TSPO
SCHEMBL11998167 0.78 L3MBTL1 (0.50) LDHAFAAHMGLLNR3C1TSPO
SCHEMBL11998159 0.78 L3MBTL1 (0.50) LDHAFAAHMGLLNR3C1TSPO
SCHEMBL17949207 0.78 PIM1 (0.38) PGRPIM1PLGPLAULDHA
SCHEMBL20825857 0.77 ESR1 (0.47) PGRPIM1LDHANR3C1TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-14 US disclosed
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same CYC1, CCNA1, CYCS PGR 607/4885PIM1 252/4885PLG 4530/4885
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS PGR 607/4885PIM1 252/4885PLG 4530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.