SCHEMBL19685895

SCHEMBL19685895

Cc1coc2cc(-n3c4ccc(-c5ccccc5)cc4c4cc(-c5ccccc5)ccc43)ccc2c1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.47
PTPN2 P17706 2/20 0.47
ALDH1A1 P00352 5/20 0.40
KDM4E B2RXH2 4/20 0.40
NPC1 O15118 4/20 0.40
RAB9A P51151 4/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
MAPT P10636 4/20 0.40
HPGD P15428 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
POLB P06746 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TOP2A P11388 3/20 0.39
USP2 O75604 1/20 0.38
HSD17B10 Q99714 1/20 0.38
GAA P10253 2/20 0.38
PTGS1 P23219 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19685689 0.91 PTPN1 (0.50) PTPN1PTPN2ALDH1A1RAB9ATOP2A
SCHEMBL19685903 0.86 KDM4E (0.40) PTPN1PTPN2ALDH1A1KDM4ENPC1
SCHEMBL19685893 0.83 ALDH1A1 (0.36) PTPN1PTPN2ALDH1A1KDM4ENPC1
SCHEMBL19685853 0.82 TNKS2 (0.37) PTPN1PTPN2TOP2ATNKS2MAOB
SCHEMBL19685803 0.77 CYP1B1 (0.43) NPC1RAB9ASMN1; SMN2MAPTHPGD
SCHEMBL19685966 0.77 NR4A2 (0.43) ALDH1A1MAPTNPSR1MAPK1TNKS2
SCHEMBL19685739 0.76 CAPN1 (0.39) TNKS2MAOB
SCHEMBL19686031 0.76 NR4A2 (0.46) ALDH1A1KMT2ATNKS2MAOB
SCHEMBL26509051 0.75 PRKDC (0.39) PTPN1PTPN2KDM4ENPC1RAB9A
SCHEMBL19686027 0.75 BRD4 (0.49) ALDH1A1KDM4EGAATNKS2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-14 US disclosed
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same CYC1, CCNA1, CYCS PTPN1 1070/4885PTPN2 2034/4885ALDH1A1 572/4885
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS PTPN1 1070/4885PTPN2 2034/4885ALDH1A1 572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.