SCHEMBL19686136

SCHEMBL19686136

Cc1coc2ccc(-n3c4ccc(N(c5ccccc5)c5ccccc5)cc4c4cc(N(c5ccccc5)c5ccccc5)ccc43)cc2c1=O

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
TSHR P16473 2/20 0.37
RAB9A P51151 1/20 0.36
PDE10A Q9Y233 7/20 0.35
APP P05067 1/20 0.34
TOP2A P11388 2/20 0.34
MAOB P27338 1/20 0.33
HSD17B10 Q99714 1/20 0.32
PTPN1 P18031 2/20 0.32
PTPN2 P17706 1/20 0.32
HTR3E A5X5Y0 1/20 0.31
HTR3B O95264 1/20 0.31
HTR3A P46098 1/20 0.31
HTR3D Q70Z44 1/20 0.31
HTR3C Q8WXA8 1/20 0.31
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19685893 0.91 ALDH1A1 (0.36) ALDH1A1TSHRRAB9APDE10AAPP
SCHEMBL19685691 0.87 ALDH1A1 (0.41) ALDH1A1TSHRRAB9AMAOBHSD17B10
SCHEMBL19685688 0.85 PDE10A (0.38) ALDH1A1TSHRRAB9APDE10ATOP2A
SCHEMBL19685851 0.83 APP (0.35) ALDH1A1APP
SCHEMBL19685855 0.83 APP (0.35) ALDH1A1APP
SCHEMBL19685689 0.83 PTPN1 (0.50) ALDH1A1TSHRRAB9APDE10ATOP2A
SCHEMBL19686281 0.80 APP (0.36) ALDH1A1APPMAOBHSD17B10
SCHEMBL19685697 0.79 ACHE (0.45) ALDH1A1APPMAOBHSD17B10CA12
SCHEMBL19685827 0.79 SCN2B (0.37) ALDH1A1APPHSD17B10
SCHEMBL19685687 0.78 PTPN1 (0.52) ALDH1A1TSHRRAB9AMAOBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-14 US disclosed
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same CYC1, CCNA1, CYCS ALDH1A1 572/4885TSHR 3571/4885RAB9A 3747/4885
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS ALDH1A1 572/4885TSHR 3571/4885RAB9A 3747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.