SCHEMBL19686253

SCHEMBL19686253

Cc1coc2ccc(N3c4ccccc4[Si]4(c5ccccc5-c5ccccc54)c4ccccc43)cc2c1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 5/20 0.34
USP2 O75604 2/20 0.34
HSD17B10 Q99714 2/20 0.34
KDM4E B2RXH2 1/20 0.34
HPGD P15428 1/20 0.34
RAB9A P51151 1/20 0.34
KCNA3 P22001 3/20 0.33
TSHR P16473 2/20 0.33
CYP17A1 P05093 1/20 0.32
HTR3E A5X5Y0 1/20 0.32
HTR3B O95264 1/20 0.32
HTR3A P46098 1/20 0.32
HTR3D Q70Z44 1/20 0.32
HTR3C Q8WXA8 1/20 0.32
CHRNA7 P36544 1/20 0.32
KCNH2 Q12809 1/20 0.32
MAOB P27338 1/20 0.32
MAP3K5 Q99683 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19686012 0.91 ALDH1A1 (0.42) MEN1KMT2AALDH1A1USP2HSD17B10
SCHEMBL19685677 0.89 ALDH1A1 (0.36) MEN1KMT2AALDH1A1USP2HSD17B10
SCHEMBL19686107 0.83 MEN1 (0.35) MEN1KMT2AALDH1A1USP2HSD17B10
SCHEMBL19686060 0.83 MEN1 (0.35) MEN1KMT2AALDH1A1USP2HSD17B10
SCHEMBL19686256 0.80 KMT2A (0.35) MEN1KMT2AALDH1A1USP2HSD17B10
SCHEMBL19686010 0.80 ALDH1A1 (0.37) MEN1KMT2AALDH1A1USP2HSD17B10
SCHEMBL19686063 0.78 ACHE (0.43) MEN1KMT2AALDH1A1HSD17B10KDM4E
SCHEMBL19685816 0.77 KMT2A (0.35) MEN1KMT2AALDH1A1KDM4ERAB9A
SCHEMBL19685733 0.76 MEN1 (0.35) MEN1KMT2AALDH1A1KDM4ERAB9A
SCHEMBL19685859 0.76 BRD4 (0.43) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-14 US disclosed
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same CYC1, CCNA1, CYCS MEN1 644/4885KMT2A 1444/4885ALDH1A1 572/4885
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS MEN1 644/4885KMT2A 1444/4885ALDH1A1 572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.