Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 5/20 | 0.48 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.44 |
| ▸ | CCR2 | P41597 | 3/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 4/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12939210 | 0.69 | CCR9 (0.55) | CCR9PLA2G10CCR2NOD2NOD1 | |
| SCHEMBL28206476 | 0.69 | CCR2 (0.64) | PLA2G10CCR2NOD2NOD1F10 | |
| SCHEMBL12930100 | 0.68 | NOD2 (0.65) | CCR9NOD2NOD1GPR35F10 | |
| SCHEMBL16480591 | 0.68 | PLA2G10 (0.48) | CCR9PLA2G10GPR35MCL1 | |
| SCHEMBL30490430 | 0.68 | CCR9 (0.70) | CCR9CCR2GPR35 | |
| SCHEMBL12930101 | 0.67 | NOD2 (0.67) | CCR9NOD2NOD1F10 | |
| SCHEMBL1573798 | 0.65 | PLA2G10 (0.78) | PLA2G10CCR2NOD2NOD1GPR35 | |
| SCHEMBL31300585 | 0.64 | PLA2G2A (0.47) | PLA2G10CCR2NOD2NOD1F10 | |
| SCHEMBL25145010 | 0.64 | CCR2 (0.67) | PLA2G10CCR2NOD2NOD1F10 | |
| SCHEMBL14693726 | 0.63 | CCR2 (0.77) | CCR9CCR2NOD2NOD1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205972-A1 | SYSTEMS METHODS AND COMPOSITIONS FOR PREDICTING METASTASIS IN BLADDER CANCER | GENOMEDX BIOSCIENCES, INC. (CA) | 2017-12-07 | — | — | WO | disclosed |