Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 13/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 3/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | RORA | P35398 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | RORB | Q92753 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19687576 | 0.83 | RAB9A (0.35) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL19687618 | 0.82 | RAB9A (0.32) | MEN1RAB9AALDH1A1 | |
| SCHEMBL30406055 | 0.82 | ALDH1A1 (0.42) | CYP1A2CYP3A4CYP2C19MEN1RAB9A | |
| SCHEMBL17596607 | 0.81 | GAA (0.37) | MEN1KMT2ARAB9APGRALDH1A1 | |
| SCHEMBL25422550 | 0.78 | RAB9A (0.36) | MEN1RAB9APGR | |
| SCHEMBL20259682 | 0.77 | HRH1 (0.38) | MEN1KMT2ARAB9A | |
| SCHEMBL17596695 | 0.76 | LMNA (0.35) | MEN1KMT2AARPGRALDH1A1 | |
| SCHEMBL23225490 | 0.75 | MEN1 (0.36) | MEN1KMT2AALDH1A1 | |
| SCHEMBL19300239 | 0.75 | PTGER4 (0.33) | MEN1KMT2ARAB9A | |
| SCHEMBL12327786 | 0.75 | AR (0.38) | CYP1A2CYP3A4CYP2C19RAB9AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205972-A1 | SYSTEMS METHODS AND COMPOSITIONS FOR PREDICTING METASTASIS IN BLADDER CANCER | GENOMEDX BIOSCIENCES, INC. (CA) | 2017-12-07 | — | — | WO | disclosed |