SCHEMBL19688093

SCHEMBL19688093

O=Cc1c(Cl)c(F)cc(F)c1Cl

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32
ERN1 O75460 2/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA13 Q8N1Q1 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22469513 0.83 GRIN2D (0.37) ALDH1A1TDP1MEN1KMT2AGRIN2D
SCHEMBL29800259 0.83 GRIN2D (0.37) ALDH1A1TDP1MEN1KMT2AGRIN2D
SCHEMBL5357933 0.80 KEAP1 (0.46) ALDH1A1ERN1CA12CA1CA2
SCHEMBL25209080 0.78 ERN1 (0.32) ALDH1A1TDP1MEN1KMT2AGRIN2D
SCHEMBL31015978 0.78 ERN1 (0.32) ALDH1A1TDP1MEN1KMT2AGRIN2D
SCHEMBL488952 0.77 ALDH1A1 (0.42) ALDH1A1TDP1MEN1KMT2AERN1
SCHEMBL7929904 0.77 KIF11 (0.32) ALDH1A1TDP1MEN1KMT2A
SCHEMBL6738427 0.76 ALDH1A1 (0.42) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL5987174 0.75 ERN1 (0.46) TDP1ERN1
SCHEMBL1349783 0.74 ERN1 (0.41) ALDH1A1TDP1MEN1KMT2AERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109195944-B Ester compound and use thereof 大日本除虫菊株式会社 2022-06-14 CN disclosed
WO-2017208632-A1 ESTER COMPOUND AND USE THEREOF 大日本除蟲菊株式会社 2017-12-07 WO disclosed