Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | EED | O75530 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19690352 | 0.95 | MAPT (0.55) | MAPTLMNAHTTSIRT6RECQL | |
| SCHEMBL19690293 | 0.92 | LMNA (0.54) | MAPTLMNAHTTSIRT6RECQL | |
| SCHEMBL19690292 | 0.85 | LMNA (0.58) | MAPTLMNAHTTSIRT6RECQL | |
| SCHEMBL19690307 | 0.81 | LMNA (0.46) | MAPTLMNAHTTRECQLMEN1 | |
| SCHEMBL19690301 | 0.80 | LMNA (0.58) | MAPTLMNAHTTSIRT6RECQL | |
| SCHEMBL19690477 | 0.77 | LMNA (0.46) | MAPTLMNAHTTRECQLMEN1 | |
| SCHEMBL19690443 | 0.76 | LMNA (0.58) | MAPTLMNAHTTSIRT6RECQL | |
| SCHEMBL19690508 | 0.76 | KDR (0.41) | MAPTHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL19695520 | 0.76 | LMNA (0.39) | MAPTLMNAHTTRECQLSMN1; SMN2 | |
| SCHEMBL331522 | 0.75 | ALDH1A1 (0.64) | MAPTLMNAMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858900-B2 | Fluorinated 2-amino-4-(substituted amino)phenyl carbamate derivatives | OCUTERRA THERAPEUTICS, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-20210309612-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | OCUTERRA THERAPEUTICS, INC. | 2021-10-07 | — | — | US | disclosed |
| EP-3468947-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | SciFluor Life Sciences, Inc. (US) | 2019-04-17 | — | — | EP | disclosed |
| US-20170355679-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | SCIFLUOR LIFE SCIENCES, INC. | 2017-12-14 | — | — | US | disclosed |
| WO-2017214539-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170355679-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | KCNQ2, KCNQ1, KCNQ3 | MAPT 2123/4885LMNA 2343/4885HTT 1584/4885 |
| US-11858900-B2 | Fluorinated 2-amino-4-(substituted amino)phenyl carbamate derivatives | KCNQ2, KCNQ1, KCNQ3 | MAPT 2123/4885LMNA 2343/4885HTT 1584/4885 |
| US-20210309612-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | KCNQ2, KCNQ1, KCNQ3 | MAPT 2123/4885LMNA 2343/4885HTT 1584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.