SCHEMBL19690519

SCHEMBL19690519

CC(C)C(C(=O)O)C(C)(C(=O)O)C(C)C

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
SLC7A5 Q01650 1/20 0.33
MAPT P10636 1/20 0.30
PTGS1 P23219 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL283644 0.79 ALDH1A1 (0.44) ALDH1A1TP53TSHRSLC7A5MAPT
SCHEMBL28704882 0.76 ALDH1A1 (0.42) ALDH1A1TP53TSHRMAPTPTGS1
SCHEMBL5514917 0.76 TP53 (0.42) ALDH1A1TP53TSHRSLC7A5MAPT
Ammonia Solution, Strong SCHEMBL5978210 0.76 ALDH1A1 (0.42) ALDH1A1TP53TSHRMAPTPTGS1
SCHEMBL13542998 0.76 TP53 (0.42) ALDH1A1TP53TSHRSLC7A5MAPT
SCHEMBL20262433 0.75 ALDH1A1 (0.36) ALDH1A1TP53TSHRSLC7A5MAPT
SCHEMBL18583195 0.75 ALDH1A1 (0.36) ALDH1A1TP53TSHRSLC7A5MAPT
SCHEMBL20262331 0.73 TP53 (0.35) ALDH1A1TP53SLC7A5
SCHEMBL14261024 0.72 ALDH1A1 (0.38) ALDH1A1TP53TSHRSLC7A5MAPT
SCHEMBL9143730 0.72 ALDH1A1 (0.38) ALDH1A1TP53TSHRSLC7A5MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3397657-B1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS BRASKEM AMERICA INC (US) 2024-06-12 EP claimed
WO-2022078492-A1 MAGNESIUM-BASED SOLID AND CATALYST COMPONENT HAVING MULTIMODAL PORE DISTRIBUTION, AND PREPARATION METHODS THEREFOR 中国石油化工股份有限公司 2022-04-21 WO disclosed
US-11136421-B2 Solid catalyst component for use in olefin polymerisation, catalyst, and application thereof BEIJING LIHE TECHNOLOGY LTD (CN) 2021-10-05 US disclosed
US-20200071430-A1 SOLID CATALYST COMPONENT FOR USE IN OLEFIN POLYMERISATION, CATALYST, AND APPLICATION THEREOF BEIJING LIHE TECH LTD (CN) 2020-03-05 US disclosed
CN-109923170-A Concentrate composition and polypropylene resin composite comprising the concentrate composition 胜亚诺盟股份有限公司 2019-06-21 CN disclosed
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF RENQIU LIHE TECH LTD (CN) 2019-06-06 US disclosed
CN-106608923-B Catalytic component and its preparation method and application and catalyst system and its application and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2019-03-26 CN disclosed
CN-108570119-A A kind of ingredient of solid catalyst containing naphthylenediamine class compound, catalyst and its application 北京利和知信科技有限公司 2018-09-25 CN disclosed
CN-108570120-A Ingredient of solid catalyst and catalyst containing o-phenylenediamine class compound and its application 北京利和知信科技有限公司 2018-09-25 CN disclosed
CN-108517022-A For the ingredient of solid catalyst and its catalyst of olefinic polymerization and application 北京利和知信科技有限公司 2018-09-11 CN disclosed
CN-101065437-B Elastomeric polyolefin compositions BASELL POLIOLEFINE SRL 2010-12-08 CN disclosed
CN-101821303-A Process for the preparation of high flow propylene polymers BASELL POLIOLEFINE SRL 2010-09-01 CN disclosed
CN-100523076-C Impact resistant polyolefin compositions BASELL POLIOLEFINE SRL (IT) 2009-08-05 CN disclosed
CN-101065437-A Elastomeric polyolefin compositions BASELL POLIOLEFINE SRL (IT) 2007-10-31 CN disclosed
CN-1294159-C Propylene polymers with high isotactic index BASSEL TECHNOLOGY B V (NL) 2007-01-10 CN disclosed
CN-1768108-A Impact resistant polyolefin compositions BASELL POLIOLEFINE SRL (IT) 2006-05-03 CN disclosed
CN-1240729-C Components and catalysts for the polymerization of olefins BASELL TECHNOLOGY CO B V (IT) 2006-02-08 CN disclosed
CN-1681853-A Components and catalysts for the polymerization of olefins BASELL POLIOLEFINE SPA (IT) 2005-10-12 CN disclosed
CN-1515597-A Propylene polymers with high isotactic index 2004-07-28 CN disclosed
CN-1313869-A Components and catalysts for the polymerization of olefins BASELL TECHNOLOGY CO B V (NL) 2001-09-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF COG2, GTF2I, POF1B ALDH1A1 2055/4885TP53 3027/4885TSHR 2613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.