Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.66 |
| ▸ | ACHE | P22303 | 6/20 | 0.66 |
| ▸ | BCHE | P06276 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19691823 | 1.00 | FAAH (0.66) | FAAHACHEBCHEKDM4ESIGMAR1 | |
| SCHEMBL19691864 | 1.00 | FAAH (0.66) | FAAHACHEBCHEKDM4ESIGMAR1 | |
| SCHEMBL19691870 | 0.95 | FAAH (0.60) | FAAHACHEBCHEKDM4ESIGMAR1 | |
| SCHEMBL19691871 | 0.94 | ACHE (0.67) | FAAHACHEBCHEKDM4ESIGMAR1 | |
| SCHEMBL19692546 | 0.93 | ACHE (0.71) | FAAHACHEBCHEKDM4ESIGMAR1 | |
| SCHEMBL19691801 | 0.93 | FAAH (0.58) | FAAHACHEBCHEKDM4ESIGMAR1 | |
| SCHEMBL19708915 | 0.93 | FAAH (0.58) | FAAHACHEBCHEKDM4ESIGMAR1 | |
| SCHEMBL19691828 | 0.93 | FAAH (0.58) | FAAHACHEBCHEKDM4ESIGMAR1 | |
| SCHEMBL19691799 | 0.93 | FAAH (0.61) | FAAHACHEBCHEHRH3LTA4H | |
| SCHEMBL19691784 | 0.92 | FAAH (0.57) | FAAHACHEBCHEKDM4ESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190144384-A1 | Chemical Compounds | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-05-16 | — | — | US | claimed |
| EP-3468948-A1 | CHEMICAL COMPOUNDS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2019-04-17 | — | — | EP | claimed |
| CN-109563034-A | Chemical compound | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-04-02 | — | — | CN | claimed |
| WO-2017212423-A1 | CHEMCICAL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-12-14 | — | — | WO | claimed |
| US-10851053-B2 | Chemical compounds | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-12-01 | — | — | US | disclosed |
| US-10851053-B2 | Chemical compounds | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-12-01 | — | — | US | disclosed |
| US-20190144384-A1 | Chemical Compounds | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-05-16 | — | — | US | disclosed |
| US-20190144384-A1 | Chemical Compounds | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-05-16 | — | — | US | disclosed |
| EP-3468948-A1 | CHEMICAL COMPOUNDS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2019-04-17 | — | — | EP | disclosed |
| CN-109563034-A | Chemical compound | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-04-02 | — | — | CN | disclosed |
| WO-2017212423-A1 | CHEMCICAL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-12-14 | — | — | WO | disclosed |
| WO-2017212423-A1 | CHEMCICAL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190144384-A1 | Chemical Compounds | ATF4, EIF2B5, HSPA5 | FAAH 4384/4885ACHE 4289/4885BCHE 2621/4885 |
| US-10851053-B2 | Chemical compounds | ATF4, EIF2B5, HSPA5 | FAAH 4384/4885ACHE 4289/4885BCHE 2621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.