Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23631421 | 0.86 | TSHR (0.42) | KDM4EALDH1A1GAALMNAKMT2A | |
| SCHEMBL5701732 | 0.82 | ADRB2 (0.40) | KDM4EALDH1A1GAAUSP2LMNA | |
| SCHEMBL20556415 | 0.82 | TSHR (0.40) | ALDH1A1KMT2ANPC1RAB9APOLB | |
| SCHEMBL8958265 | 0.82 | TSHR (0.40) | ALDH1A1KMT2ANPC1RAB9APOLB | |
| SCHEMBL8958187 | 0.80 | TSHR (0.41) | ALDH1A1GAANPC1RAB9APOLB | |
| SCHEMBL19691961 | 0.79 | ZDHHC20 (0.49) | ALDH1A1GAANPC1RAB9ATDP1 | |
| SCHEMBL15561505 | 0.78 | SMN1; SMN2 (0.40) | KDM4EALDH1A1GAALMNAKMT2A | |
| SCHEMBL21069080 | 0.74 | MEN1 (0.46) | GAAKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL18106232 | 0.74 | ZDHHC20 (0.33) | KDM4EALDH1A1GAALMNAKMT2A | |
| Ethylene Glycol SCHEMBL8958263 | 0.74 | ACHE (0.38) | ALDH1A1GAASMN1; SMN2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3469009-B1 | SOLID SUPPORT | LIFE TECH AS (NO) | 2022-04-13 | — | — | EP | disclosed |
| US-11041068-B2 | Solid support | LIFE TECHNOLOGIES AS (NO) | 2021-06-22 | — | — | US | disclosed |
| US-20190264017-A1 | SOLID SUPPORT | LIFE TECHNOLOGIES AS (NO) | 2019-08-29 | — | — | US | disclosed |
| EP-3469009-A1 | SOLID SUPPORT | Life Technologies AS (NO) | 2019-04-17 | — | — | EP | disclosed |
| WO-2017211913-A1 | SOLID SUPPORT | LIFE TECHNOLOGIES AS (NO) | 2017-12-14 | — | — | WO | disclosed |