SCHEMBL18106232

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25371614	0.85	EPHX2 (0.38)	ZDHHC20ZDHHC2EPHX2KDM4ELMNA
	SCHEMBL5622292	0.79	MEN1 (0.35)	KDM4ELMNAKMT2AALDH1A1MEN1
	SCHEMBL24133101	0.76	ACHE (0.50)	EPHX2TGM2
	SCHEMBL19691978	0.74	KDM4E (0.41)	KDM4ELMNAKMT2AALDH1A1NPC1
	SCHEMBL9353632	0.72	—	—
	Bicarbonate SCHEMBL932354	0.71	POLB (0.43)	LMNAKMT2AALDH1A1MEN1CYP3A4
	Bicarbonate SCHEMBL10762215	0.71	POLB (0.43)	LMNAKMT2AALDH1A1MEN1CYP3A4
	SCHEMBL1469535	0.70	MAPT (0.54)	ZDHHC20ZDHHC2EPHX2KDM4ELMNA
	SCHEMBL30449957	0.70	MAPT (0.54)	ZDHHC20ZDHHC2EPHX2KDM4ELMNA
	SCHEMBL4021318	0.70	MAPT (0.54)	ZDHHC20ZDHHC2EPHX2KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.