Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | APP | P05067 | 4/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.52 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134146 | 0.83 | NPC1 (0.67) | MEN1KMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL12956185 | 0.79 | NPC1 (0.67) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL9607129 | 0.78 | SMN1; SMN2 (0.50) | MEN1KMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL22360047 | 0.77 | MEN1 (0.63) | MEN1KMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL671149 | 0.76 | TTR (0.85) | MEN1KMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL17732299 | 0.76 | TTR (0.85) | MEN1KMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL671150 | 0.76 | TTR (0.85) | MEN1KMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL30807100 | 0.76 | TTR (0.85) | MEN1KMT2AALDH1A1HPGDNPSR1 | |
| SCHEMBL10575803 | 0.75 | ATP4A (0.50) | MAPTNPC1 | |
| SCHEMBL4938984 | 0.75 | NFE2L2 (0.75) | ALDH1A1HPGDMAPTAPPTTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9839640-B2 | Methods of treating eye diseases associated with inflammation and vascular proliferation | OCCURX PTY LTD (AU) | 2017-12-12 | — | — | US | disclosed |