Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 2/20 | 0.48 |
| ▸ | RARA | P10276 | 1/20 | 0.48 |
| ▸ | RARG | P13631 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL3384089 | 1.00 | DAO (0.58) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL9460609 | 0.91 | TSHR (0.64) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL931656 | 0.91 | TSHR (0.64) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL5158457 | 0.90 | ALDH1A1 (0.52) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL11650940 | 0.88 | TSHR (0.58) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL2914560 | 0.87 | TSHR (0.48) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL2321548 | 0.86 | LMNA (0.58) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL6129434 | 0.86 | LMNA (0.58) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL12981029 | 0.86 | TP53 (0.61) | TSHRRARB | |
| Phthalic Acid SCHEMBL5078833 | 0.84 | ALDH1A1 (0.54) | DAOTSHRNAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220145617-A1 | Corrugated Intumescent Composite Structure and a Method of Use | 3M INNOVATIVE PROPERTIES COMPANY | 2022-05-12 | — | — | US | disclosed |
| US-10683457-B2 | Solid composite intumescent structures for fire protection | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2020-06-16 | — | — | US | disclosed |
| US-20160272891-A1 | SOLID COMPOSITE INTUMESCENT STRUCTURES FOR FIRE PROTECTION | 3M INNOVATIVE PROPERTIES COMPANY | 2016-09-22 | — | — | US | disclosed |
| US-20110262367-A1 | INSECTICIDAL GASSING AGENT CONTAINING ACTIVE INGREDIENT IN THE FORM OF A GRANULATE | BAYER CROPSCIENCE AG (DE) | 2011-10-27 | — | — | US | disclosed |
| EP-2334171-A2 | INSECTICIDAL GASSING AGENT CONTAINING ACTIVE INGREDIENT IN THE FORM OF A GRANULATE | Bayer CropScience Aktiengesellschaft (DE) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010031507-A2 | INSECTICIDAL GASSING AGENT CONTAINING ACTIVE INGREDIENT IN THE FORM OF A GRANULATE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-03-25 | — | — | WO | disclosed |
| WO-2010031508-A2 | INSECTICIDAL GASSING AGENT CONTAINING ACTIVE INGREDIENT IN THE FORM OF WAX PARTICLES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-03-25 | — | — | WO | disclosed |
| US-7645823-B2 | Resin composition, molded product from resin composition and method for preparing resin composition | SONY CORPORATION (JP) | 2010-01-12 | — | — | US | disclosed |
| US-20070270527-A1 | Resin Composition, Molded Product From Resin Composition and Method for Preparing Resin Composition | Lerner, David, Littenberg, Krumholz & Mentlik, LLP | 2007-11-22 | — | — | US | disclosed |
| US-20070257239-A1 | Resin Composition, Molded Product Obtained From Resin Composition and Method for Preparation of Resin Composition | SONY CORPORATION (JP) | 2007-11-08 | — | — | US | disclosed |
| EP-1698658-A1 | RESIN COMPOSITION, SHAPED ARTICLE USING SUCH RESIN COMPOSITION AND METHOD FOR PRODUCING RESIN COMPOSITION | Sony Corporation (JP) | 2006-09-06 | — | — | EP | disclosed |
| EP-1690899-A1 | RESIN COMPOSITION, MOLDING THEREOF AND PROCESS FOR PRODUCING THE RESIN COMPOSITION | Sony Corporation (JP) | 2006-08-16 | — | — | EP | disclosed |
| US-5645845-A | CONTAINING PYRETHROID-TYPE COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 1997-07-08 | — | — | US | disclosed |
| EP-0693254-A1 | Gel formulations containing insecticides for vaporizer systems | BAYER AG (DE) | 1996-01-24 | — | — | EP | disclosed |