Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 2/20 | 0.48 |
| ▸ | RARA | P10276 | 1/20 | 0.48 |
| ▸ | RARG | P13631 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL1969718 | 1.00 | DAO (0.58) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL9460609 | 0.91 | TSHR (0.64) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL931656 | 0.91 | TSHR (0.64) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL5158457 | 0.90 | ALDH1A1 (0.52) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL11650940 | 0.88 | TSHR (0.58) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL2914560 | 0.87 | TSHR (0.48) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL2321548 | 0.86 | LMNA (0.58) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL6129434 | 0.86 | LMNA (0.58) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL12981029 | 0.86 | TP53 (0.61) | TSHRRARB | |
| Phthalic Acid SCHEMBL5078833 | 0.84 | ALDH1A1 (0.54) | DAOTSHRNAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200339765-A1 | Plastic Articles Containing Suspended Photochromic Dye Molecules | 1-MATERIAL INC (CA) | 2020-10-29 | — | — | US | claimed |
| EP-1214272-B1 | INORGANIC OXIDES WITH MESOPOROSITY OR COMBINED MESO-AND MICROPOROSITY AND PROCESS FOR THE PREPARATION THEREOF | UNIV DELFT TECH (NL) | 2010-10-27 | — | — | EP | claimed |
| EP-1748969-A1 | METHOD OF ENHANCING THE APPEARANCE OF A SOILED POROUS SURFACE AND MAINTENANCE THEREOF | JohnsonDiversey, Inc. (US) | 2007-02-07 | — | — | EP | claimed |
| US-7071153-B2 | Method of enhancing a soiled porous surface and maintenance thereof | JOHNSONDIVERSEY, INC. (US) | 2006-07-04 | — | — | US | claimed |
| JP-2005538842-A | — | — | 2005-12-22 | — | — | JP | claimed |
| WO-2005110946-A1 | METHOD OF ENHANCING THE APPEARANCE OF A SOILED POROUS SURFACE AND MAINTENANCE THEREOF | JOHNSONDIVERSEY, INC. (US) | 2005-11-24 | — | — | WO | claimed |
| US-20050245420-A1 | METHOD OF ENHANCING A SOILED POROUS SURFACE AND MAINTENANCE THEREOF | JOHNSONDIVERSEY, INC. (US) | 2005-11-03 | — | — | US | claimed |
| US-20050187410-A1 | Mesoporous material and use thereof for the selective oxidation of organic compounds | SHAN ZHIPING (NL) | 2005-08-25 | — | — | US | claimed |
| EP-1542799-A1 | MESOPOROUS MATERIAL AND USE THEREOF FOR THE SELECTIVE OXIDATION OF ORGANIC COMPOUNDS | ABB LUMMUS GLOBAL INC. (US) | 2005-06-22 | — | — | EP | claimed |
| US-6814950-B1 | HEATING WATER, INORGANIC OXIDE, CRYSTALLINE ZEOLITE, AND COMPOUND THAT BINDS INORGANIC OXIDE BY HYDROGEN BONDING, SELECTED FROM: TRIETHANOLAMINE, SULFOLANE, TETRAETHYLPENTAMINE, DIETHYLGYCOLDIBENZOATE, AND A GLYCOL | ABB LUMMUS GLOBAL INC. | 2004-11-09 | — | — | US | claimed |
| WO-2004026473-A1 | MESOPOROUS MATERIAL AND USE THEREOF FOR THE SELECTIVE OXIDATION OF ORGANIC COMPOUNDS | ABB LUMMUS GLOBAL INC. (US) | 2004-04-01 | — | — | WO | claimed |
| US-20030017943-A1 | Mesoporous material and use thereof for the selective oxidation of organic compounds | ABB LUMMUS GLOBAL INC. | 2003-01-23 | — | — | US | claimed |
| EP-0284302-A2 | High solids PSA compounds | BASF Aktiengesellschaft (DE) | 1988-09-28 | — | — | EP | claimed |
| US-4767813-A | High solids PSA Compounds | POLYSAR FINANCIAL SERVICES S.A. (CH) | 1988-08-30 | — | — | US | claimed |
| US-11015028-B2 | Plastic articles containing suspended photochromic dye molecules | ZHEJIANG JINGYI NEW MATERIAL TECHNOLOGY CO., LTD (CN) | 2021-05-25 | — | — | US | disclosed |
| US-20200339765-A1 | Plastic Articles Containing Suspended Photochromic Dye Molecules | 1-MATERIAL INC (CA) | 2020-10-29 | — | — | US | disclosed |
| US-10682361-B2 | Sustained release bimatoprost, bimatoprost analogs, prostamides and prostaglandins for fat reduction | ALLERGAN, INC. (US) | 2020-06-16 | — | — | US | disclosed |
| EP-0551138-A1 | Film for a light valve, and method for manufacturing the film | HANKUK GLASS INDUSTRIES, INC. (KR) | 1993-07-14 | — | — | EP | disclosed |
| EP-0105994-B1 | THERMOPLASTIC INKS FOR DECORATING PURPOSES | Corning Glass Works (US) | 1987-03-25 | — | — | EP | disclosed |
| EP-0105994-A1 | Thermoplastic inks for decorating purposes | Corning Glass Works (US) | 1984-04-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10682361-B2 | Sustained release bimatoprost, bimatoprost analogs, prostamides and prostaglandins for fat reduction | FABP4, PNLIP, PTGIS | DAO 3773/4885TSHR 2910/4885NAPRT 1232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.