SCHEMBL632532

SCHEMBL632532

NCc1ccc(CCO)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.59
TDP1 Q9NUW8 2/20 0.55
ABAT P80404 1/20 0.55
HRH3 Q9Y5N1 1/20 0.52
CA1 P00915 2/20 0.52
CA12 O43570 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
CA5A P35218 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
CA5B Q9Y2D0 1/20 0.52
LOXL2 Q9Y4K0 4/20 0.50
TSHR P16473 1/20 0.46
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 2/20 0.46
BACE1 P56817 2/20 0.46
F10 P00742 1/20 0.46
F11 P03951 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9708999 0.97 CA2 (0.56) CA2TDP1ABATHRH3CA1
SCHEMBL11137080 0.93 CA2 (0.52) CA2TDP1ABATHRH3CA1
SCHEMBL40656 0.85 CA2 (0.77) CA2TDP1HRH3CA1CA12
SCHEMBL11136679 0.85 HDAC3 (0.50) CA2TDP1ABATCA1CA12
SCHEMBL11132063 0.85 CA2 (0.45) CA2TDP1ABATHRH3CA1
SCHEMBL6612634 0.84 CA2 (0.55) CA2ABATHRH3LOXL2F10
SCHEMBL196989 0.83 TAAR1 (0.64) CA2TDP1CA1CA12CA4
SCHEMBL3456843 0.82 CA2 (0.57) CA2ABATHRH3LOXL2F10
SCHEMBL6057959 0.82 CA2 (0.72) CA2TDP1CA1CA12CA4
SCHEMBL23120606 0.80 ENPP2 (0.56) TDP1LOXL2KDM4EALDH1A1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100390261-C Compositions comprising photo-labile perfume delivery systems PROCTER & GAMBLE (US) 2008-05-28 CN claimed
CN-1553948-A Compositions comprising photo-labile perfume delivery systems 2004-12-08 CN claimed
US-20250170282-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. (US) 2025-05-29 US disclosed
CN-115666575-B Compounds and uses thereof 福宏治疗公司 2024-12-10 CN disclosed
US-20230150974-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. 2023-05-18 US disclosed
US-20230150974-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. 2023-05-18 US disclosed
US-20230150974-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. 2023-05-18 US disclosed
EP-4132529-A1 COMPOUNDS AND USES THEREOF Foghorn Therapeutics Inc. (US) 2023-02-15 EP disclosed
CN-115666575-A Compound and use thereof 福宏治疗公司 2023-01-31 CN disclosed
US-20220339303-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. 2022-10-27 US disclosed
EP-3177611-B1 OPTIONALLY FUSED HETEROCYCLYL-SUBSTITUTED DERIVATIVES OF PYRIMIDINE USEFUL FOR THE TREATMENT OF INFLAMMATORY, METABOLIC, ONCOLOGIC AND AUTOIMMUNE DISEASES NUEVOLUTION AS (DK) 2021-10-06 EP disclosed
US-5633247-A ANTIARRTHYMIA AGENT MERCK & CO., INC. (US) 1997-05-27 US disclosed
US-5616620-A HYPOTENSIVE AGENTS KARL THOMAE GMBH (DE) 1997-04-01 US disclosed
CN-1034204-C Substituted quinolines and cinnolines LILLY CO ELI (US) 1997-03-12 CN disclosed
EP-0680469-A1 AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME Dr. Karl Thomae GmbH (DE) 1995-11-08 EP disclosed
CN-1110685-A Nitrogen-containing spiro ring MERCK & CO INC (US) 1995-10-25 CN disclosed
WO-1994017035-A1 AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME DR. KARL THOMAE GMBH (DE) 1994-08-04 WO disclosed
US-5206240-A Antiarrhythmia agents MERCK & CO., INC. (US) 1993-04-27 US disclosed
CN-1053613-A Nitrogen-containing spiro ring MERCK & CO INC (US) 1991-08-07 CN disclosed
EP-0431943-A2 Nitrogen-containing spirocycles MERCK & CO. INC. (US) 1991-06-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150974-A1 COMPOUNDS AND USES THEREOF VHL, CLN6, TFEB CA2 4715/4885TDP1 725/4885ABAT 120/4885
US-20250170282-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS FABP3, TNNI3, TNNT2 CA2 992/4885TDP1 1114/4885ABAT 3259/4885
US-20220339303-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS FABP3, TNNI3, TNNT2 CA2 992/4885TDP1 1114/4885ABAT 3259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.