SCHEMBL196998

SCHEMBL196998

O=C1C=C(Cl)C(=O)c2c(O)ccc(O)c21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AURKA O14965 2/20 0.61
AURKB Q96GD4 2/20 0.61
MAPT P10636 6/20 0.59
KMT2A Q03164 6/20 0.59
MEN1 O00255 5/20 0.59
KDM4E B2RXH2 5/20 0.59
RECQL P46063 5/20 0.59
MAPK1 P28482 4/20 0.59
POLB P06746 4/20 0.59
ALDH1A1 P00352 3/20 0.59
USP2 O75604 3/20 0.59
BLM P54132 3/20 0.59
TXNRD1 Q16881 2/20 0.59
THRB P10828 2/20 0.59
NPC1 O15118 1/20 0.59
GAA P10253 1/20 0.59
RAB9A P51151 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
PIM1 P11309 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30003603 1.00 AURKA (0.61) AURKAAURKBMAPTKMT2AMEN1
SCHEMBL9282104 0.91 MAPT (0.55) AURKAAURKBMAPTKMT2AMEN1
SCHEMBL23271666 0.78 AURKA (0.47) AURKAAURKBMAPTKMT2AMEN1
SCHEMBL30002972 0.78 AURKA (0.47) AURKAAURKBMAPTKMT2AMEN1
SCHEMBL5818746 0.77 MAPT (0.63) AURKAAURKBMAPTKMT2AMEN1
SCHEMBL29791770 0.77 MAPT (0.63) AURKAAURKBMAPTKMT2AMEN1
SCHEMBL30004050 0.76 AURKA (0.74) AURKAAURKBMAPTKMT2AMEN1
SCHEMBL5084612 0.76 AURKA (0.74) AURKAAURKBMAPTKMT2AMEN1
SCHEMBL2957896 0.76 AURKA (1.00) AURKAAURKBMAPTKMT2AMEN1
SCHEMBL9271153 0.74 P4HB (0.61) AURKAAURKBMAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110392529-A Stress tolerance in plants inducer 株式会社目立康 2019-10-29 CN claimed
CN-101910345-B Pressure-sensitive adhesive compositions, polarizers and liquid crystal displays comprising the same LG CHEMICAL LTD 2013-03-27 CN claimed
CN-101910345-A Pressure-sensitive adhesive compositions, polarizers and liquid crystal displays comprising the same LG CHEMICAL LTD 2010-12-08 CN claimed
EP-0498707-B1 Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent OREAL (FR) 1995-08-02 EP claimed
US-5424421-A Synthesis of carminic acid and principal intermediates EUROPEAN COLOUR PLC (GB) 1995-06-13 US claimed
US-5358538-A Treating a sugar, protein or polyamide with a naphthoquinone compound IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1994-10-25 US claimed
EP-0498707-A1 Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent L'OREAL (FR) 1992-08-12 EP claimed
US-11613509-B2 Radical polymerization control agent and radical polymerization control method KAWASAKI KASEI CHEMICALS LTD. (JP) 2023-03-28 US disclosed
CN-110891980-B Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2022-09-30 CN disclosed
US-20210122692-A1 RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD KAWASAKI KASEI CHEMICALS LTD. (JP) 2021-04-29 US disclosed
CN-110891980-A Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2020-03-17 CN disclosed
CN-106575793-B Non-aqueous secondary batteries electrolyte and the non-aqueous secondary batteries for using it 国立研究开发法人产业技术综合研究所 2019-11-22 CN disclosed
CN-110392529-A Stress tolerance in plants inducer 株式会社目立康 2019-10-29 CN disclosed
WO-2000020626-A1 SMALL VOLUME IN VITRO ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR THERASENSE, INC. (US) 2000-04-13 WO disclosed
EP-0500942-B1 PROCESS FOR PRODUCING BLACK COLORANT, COSMETIC CONTAINING SAID COLORANT, AND APPLICATION THEREOF IHARA CHEMICAL IND CO (JP) 1997-06-11 EP disclosed
EP-0498707-B1 Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent OREAL (FR) 1995-08-02 EP disclosed
US-5358538-A Treating a sugar, protein or polyamide with a naphthoquinone compound IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1994-10-25 US disclosed
US-5275626-A Hair dyes L'OREAL (FR) 1994-01-04 US disclosed
EP-0500942-A1 PROCESS FOR PRODUCING BLACK COLORANT, COSMETIC CONTAINING SAID COLORANT, AND APPLICATION THEREOF IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1992-09-02 EP disclosed
EP-0498707-A1 Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent L'OREAL (FR) 1992-08-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11613509-B2 Radical polymerization control agent and radical polymerization control method PPOX, NOX4, CROCC AURKA 4410/4885AURKB 4561/4885MAPT 188/4885
US-20210122692-A1 RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD PPOX, NOX4, CROCC AURKA 4410/4885AURKB 4561/4885MAPT 188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.