Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 2/20 | 1.00 |
| ▸ | AURKB | Q96GD4 | 2/20 | 1.00 |
| ▸ | P4HB | P07237 | 11/20 | 0.64 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | BACE1 | P56817 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | RECQL | P46063 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5084612 | 0.85 | AURKA (0.74) | AURKAAURKBP4HBMAOABACE1 | |
| SCHEMBL30004050 | 0.85 | AURKA (0.74) | AURKAAURKBP4HBMAOABACE1 | |
| SCHEMBL5175867 | 0.81 | MAPT (0.72) | AURKAAURKBP4HBMAOABACE1 | |
| SCHEMBL29728494 | 0.81 | MAPT (0.72) | AURKAAURKBP4HBMAOABACE1 | |
| SCHEMBL24389157 | 0.78 | P4HB (0.64) | AURKAAURKBP4HBMAOABACE1 | |
| SCHEMBL29440907 | 0.78 | MAPT (0.74) | AURKAAURKBP4HBMAOABACE1 | |
| SCHEMBL4304001 | 0.78 | MAPT (0.74) | AURKAAURKBP4HBMAOABACE1 | |
| SCHEMBL868197 | 0.78 | P4HB (1.00) | AURKAAURKBP4HBMAOABACE1 | |
| SCHEMBL16879551 | 0.78 | P4HB (0.64) | AURKAAURKBP4HBMAOABACE1 | |
| SCHEMBL29647673 | 0.78 | P4HB (1.00) | AURKAAURKBP4HBMAOABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1106375-C | Method for preparing substd. anthraguinone and application to preparation of rheins | GIREX (FR) | 2003-04-23 | — | — | CN | claimed |
| EP-0909268-B1 | METHOD FOR PREPARING SUBSTITUTED ANTHRAQUINONE AND APPLICATION TO THE PREPARATION OF RHEINS | GIREX (FR) | 2002-06-05 | — | — | EP | claimed |
| US-6057461-A | Method for preparing substituted anthraquinone and application to the preparation of rheins | GIREX (FR) | 2000-05-02 | — | — | US | claimed |
| US-5948924-A | Process for the preparation of substituted anthraquinones and application in the preparation of rheins | GIREX (SOCIETE ANONYME) (FR) | 1999-09-07 | — | — | US | claimed |
| CN-1216035-A | METHOD FOR PREPARING SUBSTD. ANTHRAGUINONE AND APPLICATION TO PREPARATION OF RHEINS | GIREX (FR) | 1999-05-05 | — | — | CN | claimed |
| US-4895575-A | HAIR DYES | L'OREAL (FR) | 1990-01-23 | — | — | US | claimed |
| CN-114276227-B | Aurora kinase inhibitor and application thereof in preparation of antitumor drugs | 山东省千佛山医院 | 2023-10-13 | — | — | CN | disclosed |
| CN-105985242-A | Preparation method of diacerein | 邵阳学院 | 2016-10-05 | — | — | CN | disclosed |
| US-7763740-B2 | Method for the production of mumbaistatin derivatives | SANOFI-AVENTIS (FR) | 2010-07-27 | — | — | US | disclosed |
| US-20090156836-A1 | METHOD FOR THE PRODUCTION OF MUMBAISTATIN DERIVATIVES | SANOFI-AVENTIS (FR) | 2009-06-18 | — | — | US | disclosed |
| CN-101421222-A | Process for the preparation of Mumbaistatin derivatives | SANOFI AVENTIS (FR) | 2009-04-29 | — | — | CN | disclosed |
| EP-2010474-A1 | METHOD FOR THE PRODUCTION OF MUMBAISTATIN DERIVATIVES | Sanofi-Aventis (FR) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007121822-A1 | METHOD FOR THE PRODUCTION OF MUMBAISTATIN DERIVATIVES | SANOFI-AVENTIS (DE) | 2007-11-01 | — | — | WO | disclosed |
| US-5948924-A | Process for the preparation of substituted anthraquinones and application in the preparation of rheins | GIREX (SOCIETE ANONYME) (FR) | 1999-09-07 | — | — | US | disclosed |
| CN-1216035-A | METHOD FOR PREPARING SUBSTD. ANTHRAGUINONE AND APPLICATION TO PREPARATION OF RHEINS | GIREX (FR) | 1999-05-05 | — | — | CN | disclosed |
| EP-0909268-A1 | METHOD FOR PREPARING SUBSTITUTED ANTHRAQUINONE AND APPLICATION TO THE PREPARATION OF RHEINS | Girex (FR) | 1999-04-21 | — | — | EP | disclosed |
| WO-1998033757-A1 | METHOD FOR PREPARING SUBSTITUTED ANTHRAQUINONE AND APPLICATION TO THE PREPARATION OF RHEINS | GIREX (FR) | 1998-08-06 | — | — | WO | disclosed |
| EP-0801639-A1 | METHOD FOR PREPARING SUBSTITUTED ANTHRAQUINONES AND USE THEREOF FOR PREPARING RHEINS | Girex (FR) | 1997-10-22 | — | — | EP | disclosed |
| WO-1997016404-A1 | METHOD FOR PREPARING SUBSTITUTED ANTHRAQUINONES AND USE THEREOF FOR PREPARING RHEINS | GIREX (FR) | 1997-05-09 | — | — | WO | disclosed |
| US-4895575-A | HAIR DYES | L'OREAL (FR) | 1990-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156836-A1 | METHOD FOR THE PRODUCTION OF MUMBAISTATIN DERIVATIVES | MMAB, MLYCD, HMBS | AURKA 50/4885AURKB 9/4885P4HB 354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.