Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 5/20 | 0.52 |
| ▸ | CHUK | O15111 | 3/20 | 0.52 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 4/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.46 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1512152 | 0.91 | BCAT2 (0.59) | IKBKBCHUKBCAT2PARP1FGFR1 | |
| SCHEMBL29184001 | 0.86 | G6PD (0.50) | IKBKBCHUKBCAT2SLC6A4SLC6A3 | |
| SCHEMBL3791160 | 0.86 | BCAT2 (0.53) | IKBKBCHUKBCAT2PARP1FGFR1 | |
| SCHEMBL197002 | 0.84 | BCAT2 (0.71) | IKBKBCHUKBCAT2SLC6A4SLC6A3 | |
| SCHEMBL3433069 | 0.84 | BCAT2 (0.71) | IKBKBCHUKBCAT2PARP1KEAP1 | |
| SCHEMBL28282551 | 0.83 | BCAT2 (0.50) | IKBKBCHUKBCAT2PARP1FGFR1 | |
| SCHEMBL28270443 | 0.82 | BCAT2 (0.69) | IKBKBCHUKBCAT2SLC6A4SLC6A3 | |
| SCHEMBL7143118 | 0.79 | CHUK (0.61) | IKBKBCHUKBCAT2PARP1CASP1 | |
| SCHEMBL30903677 | 0.79 | IKBKB (0.64) | IKBKBCHUKBCAT2PTGS1PTGS2 | |
| SCHEMBL1512155 | 0.77 | BCAT2 (0.55) | IKBKBCHUKBCAT2PARP1FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1143855-C | I (ortho)-anthranilamide derivatives as anti-coagulants | ���ֹɷݹ�˾ | 2004-03-31 | — | — | CN | disclosed |
| EP-1040108-B1 | ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS | SCHERING AG (DE) | 2004-02-25 | — | — | EP | disclosed |
| US-6498185-B1 | ENZYME FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. | 2002-12-24 | — | — | US | disclosed |
| CN-1282329-A | I (ortho)-anthranilamide derivatives as anti-coagulants | SCHERING AG (DE) | 2001-01-31 | — | — | CN | disclosed |
| US-6140351-A | FOR TREATING THROMBOSIS | BERLEX LABORATORIES, INC. (US) | 2000-10-31 | — | — | US | disclosed |