SCHEMBL197035

SCHEMBL197035

COc1ccccc1-c1nc(N(C)OC)nc(N(OC)OC)n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.49
HSD17B10 Q99714 7/20 0.49
TSHR P16473 7/20 0.49
TP53 P04637 6/20 0.49
CYP1A2 P05177 5/20 0.49
CYP3A4 P08684 5/20 0.49
CYP2D6 P10635 5/20 0.49
LMNA P02545 4/20 0.49
USP2 O75604 2/20 0.49
ALOX15 P16050 2/20 0.49
SMN1; SMN2 Q16637 10/20 0.46
RAB9A P51151 7/20 0.46
NPC1 O15118 6/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
KDM4E B2RXH2 4/20 0.43
CYP2C19 P33261 3/20 0.43
MAPK1 P28482 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
GAA P10253 2/20 0.42
HPGD P15428 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23066466 0.76 ALDH1A1 (0.61) ALDH1A1HSD17B10TSHRTP53CYP1A2
SCHEMBL4597287 0.70 L3MBTL1 (0.47) ALDH1A1HSD17B10TSHRTP53CYP1A2
SCHEMBL2746732 0.69 NPSR1 (0.42) ALDH1A1HSD17B10TSHRLMNAUSP2
SCHEMBL11405229 0.68 ALDH1A1 (0.52) ALDH1A1HSD17B10TSHRTP53CYP1A2
SCHEMBL3678540 0.68 HSP90AA1 (0.58) ALDH1A1HSD17B10TSHRTP53CYP1A2
SCHEMBL4063280 0.67 TP53 (0.48) ALDH1A1HSD17B10TP53CYP1A2LMNA
SCHEMBL10645528 0.67 ADORA3 (0.52) ALDH1A1HSD17B10TSHRTP53CYP1A2
SCHEMBL10646200 0.67 HSP90AA1 (0.59) ALDH1A1HSD17B10TSHRTP53CYP1A2
SCHEMBL10345022 0.67 HSD17B10 (0.54) ALDH1A1HSD17B10TSHRTP53CYP1A2
SCHEMBL4467732 0.67 MAPK1 (0.56) ALDH1A1HSD17B10TSHRTP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 683 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10822518-B2 Curable coating compositions using succinic acid LCY BIOSCIENCES INC. (CA) 2020-11-03 US claimed
WO-2018231599-A1 SELF-CURABLE AND LOW TEMPERATURE CURABLE POLYESTERS EASTMAN CHEMICAL COMPANY (US) 2018-12-20 WO claimed
US-20180355105-A1 SELF-CUREABLE AND LOW TEMPERATURE CUREABLE POLYESTERS EASTMAN CHEMICAL COMPANY (US) 2018-12-13 US claimed
US-20180258314-A1 CURABLE COATING COMPOSITIONS USING SUCCINIC ACID LCY BIOSCIENCES INC. (CA) 2018-09-13 US claimed
EP-3350241-A1 CURABLE COATING COMPOSITIONS USING SUCCINIC ACID BioAmber Inc. (US) 2018-07-25 EP claimed
WO-2017048767-A1 CURABLE COATING COMPOSITIONS USING SUCCINIC ACID BIOAMBER INC. (US) 2017-03-23 WO claimed
EP-2603566-B1 THERMOSETTING COATING COMPOSITION EASTMAN CHEM CO (US) 2017-02-15 EP claimed
US-9029461-B2 Aliphatic polyester coating compositions containing tetramethyl cyclobutanediol EASTMAN CHEMICAL COMPANY (US) 2015-05-12 US claimed
US-9029460-B2 Coating compositions containing acrylic and aliphatic polyester blends EASTMAN CHEMICAL COMPANY 2015-05-12 US claimed
US-8969489-B2 Thermosetting coating composition EASTMAN CHEMICAL COMPANY (US) 2015-03-03 US claimed
EP-0668334-B1 Powder coating composition and method of coating a substrate therewith CYTEC TECH CORP (US) 1998-12-30 EP claimed
EP-0572530-B1 THERMOSETTING COATING COMPOSITIONS EASTMAN CHEM CO (US) 1995-04-26 EP claimed
WO-1994014871-A1 POLYESTER COATINGS CONTAINING COVALENTLY-BOUND MESOGENIC MONOMERS EASTMAN KODAK COMPANY (US) 1994-07-07 WO claimed
US-5324788-A A copolymer of a 4-acyloxystyrene and an acrylate modified by an alcohol to effect an ester interchange, an aminoplast crosslinking agent and solvent; enamel coatings; acid and solvent resistance; hardness; gloss; autos EASTMAN KODAK COMPANY (US) 1994-06-28 US claimed
US-5256761-A Polyester coatings containing covalently-bound mesogenic monomers EASTMAN KODAK COMPANY (US) 1993-10-26 US claimed
US-5144003-A Curable copolymers containing 1,5-bis(4-carboxycyclohexyl)-3-pentanol monomer; castings and moldings EASTMAN KODAK COMPANY (US) 1992-09-01 US claimed
EP-0008156-B1 PRODUCTION OF POLYMER MICROPARTICLES AND COATING COMPOSITIONS CONTAINING THEM IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-03-14 EP claimed
US-4379909-A Coating compositions HERMANN WIEDERHOLD GMBH CORP. (DE) 1983-04-12 US claimed
US-4340511-A AMINO RESIN CROSSLINKED ADDITION POLYMER IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1982-07-20 US claimed
EP-0008156-A1 Production of polymer microparticles and coating compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-02-20 EP claimed